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1. (WO1999041274) A METHOD FOR THE REMOVAL OF CAUSATIVE AGENT(S) OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES FROM PROTEIN SOLUTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/041274    International Application No.:    PCT/EP1998/008166
Publication Date: 19.08.1999 International Filing Date: 14.12.1998
Chapter 2 Demand Filed:    12.08.1999    
IPC:
B01D 15/00 (2006.01), C07K 14/47 (2006.01)
Applicants: ROTKREUZSTIFTUNG ZENTRALLABORATORIUM BLUTSPENDEDIENST SRK [CH/CH]; Wankdorfstrasse 10, CH-3000 Bern 22 (CH) (For All Designated States Except US).
MORGENTHALER, Jean-Jacques [CH/CH]; (CH) (For US Only).
MARING, Jacques-Andre [CH/CH]; (CH) (For US Only).
RENTSCH, Markus [CH/CH]; (CH) (For US Only)
Inventors: MORGENTHALER, Jean-Jacques; (CH).
MARING, Jacques-Andre; (CH).
RENTSCH, Markus; (CH)
Agent: BOVARD LTD.; Optingenstrasse 16, CH-3000 Bern 25 (CH)
Priority Data:
98810108.5 11.02.1998 EP
Title (EN) A METHOD FOR THE REMOVAL OF CAUSATIVE AGENT(S) OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES FROM PROTEIN SOLUTIONS
(FR) PROCEDE D'ELIMINATION DU OU DES AGENTS ETIOLOGIQUES DES ENCEPHALOPATHIES SPONGIFORMES TRANSMISSIBLES, DE SOLUTIONS PROTEIQUES
Abstract: front page image
(EN)For separating non-conventional transmissible agents (NCTAs), i.e. causative agent(s), of transmissible spongiform encephalopathies (TSEs) from a solution of a protein susceptible to contamination with NCTAs, particularly from blood products, at least one adsorbent is suspended, for a time of at least 10 minutes. The absorbent is selected from kieselguhr, diatomaceous earth, silicic acid, clay minerals, metal hydroxide, metal oxihydrate, cellulose, perlite, bentonite, and water-insoluble synthetic polymers. The obtained suspension is agitated, and subsequently the adsorbent is separated from the protein solution.
(FR)Pour la séparation d'agents transmissibles non conventionnels, c'est-à-dire le(s) agent(s) étiologique(s) d'encéphalopathies spongiformes transmissibles, d'une solution de protéine susceptible d'être contaminée par lesdits agents, notamment de produits sanguins, au moins un adsorbant est suspendu, pendant au moins 10 minutes. L'adsorbant est sélectionné parmi kieselguhr, la terre de diatomées, l'acide silicique, les argiles, l'hydroxyde de métal, l'oxyhydrate de métal, la cellulose, la perlite, la bentonite et des polymères synthétiques insolubles dans l'eau. La suspension obtenue est agitée, après quoi l'adsorbant est séparé de la solution protéique.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)