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1. (WO1999041271) HIGH AFFINITY NUCLEIC ACID LIGANDS OF COMPLEMENT SYSTEM PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/041271    International Application No.:    PCT/US1999/002597
Publication Date: 19.08.1999 International Filing Date: 05.02.1999
Chapter 2 Demand Filed:    19.08.1999    
IPC:
C07B 61/00 (2006.01), C07H 21/00 (2006.01), C12N 15/11 (2006.01), C12Q 1/68 (2006.01)
Applicants: NEXSTAR PHARMACEUTICALS, INC. [US/US]; Suite 200 2860 Wilderness Place Boulder, CO 80301 (US)
Inventors: BIESECKER, Gregory; (US).
GOLD, Larry; (US)
Agent: SWANSON, Barry, J.; Swanson & Bratschun, L.L.C. Suite 330 1745 Shea Center Drive Highlands Ranch, CO 80126 (US)
Priority Data:
09/023,228 12.02.1998 US
09/163,025 29.09.1998 US
Title (EN) HIGH AFFINITY NUCLEIC ACID LIGANDS OF COMPLEMENT SYSTEM PROTEINS
(FR) LIGANDS A FORTE AFFINITE D'ACIDES NUCLEIQUES DE PROTEINES DU SYSTEME COMPLEMENTAIRE
Abstract: front page image
(EN)Methods are described for the identification and preparation of high-affinity Nucleic Acid Ligands to Complement System Proteins. Methods are described for the identification and preparation of high affinity Nucleic Acid Ligands to Complement System Proteins C1q, C3 and C5. Included in the invention are specific RNA ligands to C1q, C3 and C5 identified by the SELEX method.
(FR)L'invention concerne des procédés d'identification et de préparation de ligands à forte affinité d'acides nucléiques de protéines du système complémentaire. Ces procédés consistent à identifier et préparer des ligands à forte affinité d'acides nucléiques des protéines C1q, C3 et C5 du système complémentaire. L'invention concerne également des ligands d'ARN spécifiques des protéines C1q, C3 et C5, identifiés selon le processus SELEX.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)