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1. (WO1999040443) METHOD FOR THE DETERMINATION OF OXIDATIVE STRESS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/040443    International Application No.:    PCT/US1999/001853
Publication Date: 12.08.1999 International Filing Date: 03.02.1999
Chapter 2 Demand Filed:    06.09.1999    
IPC:
G01N 33/68 (2006.01)
Applicants: WASHINGTON UNIVERSITY [US/US]; One Brookings Drive St. Louis, MO 63130 (US) (For All Designated States Except US).
HEINECKE, Jay, W. [US/US]; (US) (For US Only)
Inventors: HEINECKE, Jay, W.; (US)
Agent: MEYER, Scott, J.; G.D. Searle & Co. Corporate Patent Dept. P.O. Box 5110 Chicago, IL 60680-5110 (US).
BEIL, Hans, C.; Adelonstrasse 58 Postfach 80 01 40 D-65901 Frankfurt am Main (DE)
Priority Data:
60/074,167 09.02.1998 US
Title (EN) METHOD FOR THE DETERMINATION OF OXIDATIVE STRESS
(FR) PROCEDE DE DETERMINATION DE DOMMMAGES DUS A L'OXYDATION
Abstract: front page image
(EN)A noninvasive method for the determination of oxidative stress in a patient is disclosed. The method comprises quantifying the levels or relative distribution of a pair of compounds, $i(o, o')-dityrosine and $i(o)-tyrosine, in a sample of the patient's urine and comparing with the corresponding levels or relative distribution of said compounds in a normal or control sample.
(FR)L'invention concerne un procédé non effractif de détermination de dommages dus à l'oxydation chez un patient. Ce procédé consiste à quantifier les niveaux ou la répartition relative d'une paire de composés, à savoir $i(o,o')-dityrosine et $i(o)-tyrosine, dans un échantillon de l'urine du patient, et à comparer ces niveaux ou cette répartition relative avec ceux ou celle desdits composés dans un échantillon normal ou témoin.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)