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1. (WO1999040188) TUMOR-ASSOCIATED ANTIGEN DERIVATIVES FROM THE MAGE FAMILY, AND NUCLEIC ACID SEQUENCES ENCODING THEM, USED FOR THE PREPARATION OF FUSION PROTEINS AND OF COMPOSITIONS FOR VACCINATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/040188    International Application No.:    PCT/EP1999/000660
Publication Date: 12.08.1999 International Filing Date: 02.02.1999
Chapter 2 Demand Filed:    17.08.1999    
IPC:
A61K 38/00 (2006.01), A61K 39/00 (2006.01), A61K 48/00 (2006.01), C07K 14/11 (2006.01), C07K 14/245 (2006.01), C07K 14/285 (2006.01), C07K 14/315 (2006.01), C07K 14/47 (2006.01)
Applicants: SMITHKLINE BEECHAM BIOLOGICALS S.A. [BE/BE]; Rue de l'Institut 89, B-1330 Rixensart (BE) (For All Designated States Except US).
CABEZON SILVA, Teresa [BE/BE]; (BE) (For US Only).
COHEN, Joseph [US/BE]; (BE) (For US Only).
SLAOUI, Moncef, Mohamed [BE/BE]; (BE) (For US Only).
VINALS BASSOLS, Carlota [BE/BE]; (BE) (For US Only)
Inventors: CABEZON SILVA, Teresa; (BE).
COHEN, Joseph; (BE).
SLAOUI, Moncef, Mohamed; (BE).
VINALS BASSOLS, Carlota; (BE)
Agent: DALTON, Marcus, Jonathan, William; SmithKline Beecham, Corporate Intellectual Property, Two New Horizons Court, Brentford, Middlesex TW8 9EP (GB)
Priority Data:
9802543.0 05.02.1998 GB
9802650.3 06.02.1998 GB
Title (EN) TUMOR-ASSOCIATED ANTIGEN DERIVATIVES FROM THE MAGE FAMILY, AND NUCLEIC ACID SEQUENCES ENCODING THEM, USED FOR THE PREPARATION OF FUSION PROTEINS AND OF COMPOSITIONS FOR VACCINATIONS
(FR) DERIVES ANTIGENES ASSOCIES AUX TUMEURS DE LA FAMILLE MAGE, ET SEQUENCES D'ACIDES NUCLEIQUES CODANT CES DERIVES, UTILISES POUR LA PREPARAITON DE PROTEINES DE FUSION ET DE COMPOSITIONS DESTINEES A LA VACCINATION
Abstract: front page image
(EN)The present invention relates to novel proteins and to their production, from the MAGE family. In particular, to a MAGE protein fused to an immunological fusion partner, such as Lipoprotein D. Such antigens may be formulated to provide vaccines for the treatment of a range of tumours. Novel methods for purifying MAGE proteins are also provided.
(FR)L'invention concerne de nouvelles protéines de la famille MAGE et leur production, en particulier une protéine MAGE fusionnée à un partenaire de fusion immunologique, tel qu'une lipoprotéine D. Ces antigènes peuvent être formulés en vue d'obtenir des vaccins pour le traitement de toute une gamme de tumeurs. De nouveaux procédés de purification de protéines MAGE sont également décrits.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)