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Machine translation
1. (WO1999040079) SYNTHESIS OF DYSIDIOLIDE AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/040079    International Application No.:    PCT/US1999/002347
Publication Date: 12.08.1999 International Filing Date: 04.02.1999
Chapter 2 Demand Filed:    27.08.1999    
IPC:
A61K 31/365 (2006.01), C07C 33/14 (2006.01), C07C 45/59 (2006.01), C07C 47/45 (2006.01), C07D 307/60 (2006.01), C07F 7/18 (2006.01)
Applicants: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH [US/US]; 1275 York Avenue New York, NY 10021 (US) (For All Designated States Except US).
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US/US]; West 116th Street and Broadway New York, NY 10027 (US) (For All Designated States Except US).
DANISHEFSKY, Samuel, J. [US/US]; (US) (For US Only).
MAGNUSON, Steven, R. [CA/US]; (US) (For US Only).
ROSEN, Neal [US/US]; (US) (For US Only).
SEPP-LORENZINO, Laura [US/US]; (US) (For US Only)
Inventors: DANISHEFSKY, Samuel, J.; (US).
MAGNUSON, Steven, R.; (US).
ROSEN, Neal; (US).
SEPP-LORENZINO, Laura; (US)
Agent: WHITE, John, P.; Cooper & Dunham LLP 1185 Avenue of the Americas New York, NY 10036 (US)
Priority Data:
60/073,699 04.02.1998 US
Title (EN) SYNTHESIS OF DYSIDIOLIDE AND USES THEREOF
(FR) SYNTHESE DE DYSIDIOLIDE ET SES UTILISATIONS
Abstract: front page image
(EN)This invention provides a process for the preparation of a racemic mixture of dysidiolide a method for inhibiting growth of cancerous cells comprising contracting an amount of the racemic mixture of dysidiolide effective to inhibit the growth of said cells. Further provided is a method for treating cancer in a subject which comprises administering to the subject a therapeutically effective amount of the racemic mixture of dysidiolide.
(FR)La présente invention concerne un procédé de préparation d'un mélange racémique de dysidiolide et une méthode d'inhibition de la croissance de cellules cancéreuses, la méthode consistant à les mettre en contact avec une quantité du mélange racémique effective pour inhiber la croissance des cellules. L'invention concerne en outre une méthode de traitement du cancer chez un sujet, la méthode consistant à administrer au sujet une quantité efficace sur le plan thérapeutique du mélange racémique de dysidiolide.
Designated States: AU, CA, JP, MX, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)