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Machine translation
1. (WO1999038880) GENETIC IMMUNIZATION WITH NONSTRUCTURAL PROTEINS OF HEPATITIS C VIRUS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/038880    International Application No.:    PCT/US1999/001823
Publication Date: 05.08.1999 International Filing Date: 28.01.1999
Chapter 2 Demand Filed:    25.08.1999    
IPC:
A61K 39/00 (2006.01), C07K 14/18 (2006.01)
Applicants: THE GENERAL HOSPITAL CORPORATION [US/US]; 55 Fruit Street Boston, MA 02114 (US) (For All Designated States Except US).
WANDS, Jack [US/US]; (US) (For US Only).
ENCKE, Jens [DE/US]; (US) (For US Only)
Inventors: WANDS, Jack; (US).
ENCKE, Jens; (US)
Agent: DELUCA, Mark; Woodcock Washburn Kurtz Mackiewicz & Norris LLP 46th floor One Liberty Place Philadelphia, PA 19103 (US)
Priority Data:
60/073,156 30.01.1998 US
Title (EN) GENETIC IMMUNIZATION WITH NONSTRUCTURAL PROTEINS OF HEPATITIS C VIRUS
(FR) IMMUNISATION GENETIQUE AVEC DES PROTEINES NON STRUCTURALES DU VIRUS DE L'HEPATITE C
Abstract: front page image
(EN)Nucleic acid molecules that comprise a hepatitis C nonstructural protein including specifically disclosed DNA sequences are disclosed. Pharmaceutical compositions that contain nucleic acid molecules comprising a hepatitis C nonstructural protein including a nucleotide sequence encoding NS3, NS4, or NS5, or a combination thereof, operably linked to regulatory elements functional in human cells are disclosed. Methods of immunizing individuals susceptible to or infected by hepatitis C virus comprising administering such pharmaceutical compositions are disclosed.
(FR)L'invention concerne une molécule d'acide nucléique comprenant une protéine non structurale de l'hépatite C, y compris en particulier des séquences d'ADN. L'invention concerne également des compositions pharmaceutiques contenant des molécules d'acide nucléique comprenant une protéine non structurale de l'hépatite C y compris une séquence nucléotidique codant NS3, NS4 ou NS5 ou une combinaison de ces dernières, liée de manière fonctionnelle à des éléments régulateurs fonctionnels dans des cellules humaines. L'invention concerne en outre des méthodes d'immunisation d'individus infectés ou susceptibles d'être infectés par le virus de l'hépatite C, les méthodes consistant à administrer les compositions pharmaceutiques.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)