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Machine translation
1. (WO1999038821) TRANSFECTING COMPOSITIONS SENSITIVE TO REDUCING CONDITIONS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR APPLICATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/038821    International Application No.:    PCT/FR1999/000162
Publication Date: 05.08.1999 International Filing Date: 28.01.1999
Chapter 2 Demand Filed:    04.08.1999    
IPC:
A61K 48/00 (2006.01), C07C 323/60 (2006.01), C07K 5/06 (2006.01), C12N 15/87 (2006.01)
Applicants: AVENTIS PHARMA S.A. [FR/FR]; 20, avenue Raymond Aron F-92160 Antony (FR) (For All Designated States Except US).
BYK, Gérardo [IL/IL]; (IL) (For US Only).
DUBERTRET, Catherine [FR/FR]; (FR) (For US Only).
PITARD, Bruno [FR/FR]; (FR) (For US Only).
SCHERMAN, Daniel [FR/FR]; (FR) (For US Only)
Inventors: BYK, Gérardo; (IL).
DUBERTRET, Catherine; (FR).
PITARD, Bruno; (FR).
SCHERMAN, Daniel; (FR)
Agent: NIEDERST, Claire; Aventis Pharma S.A. 20, avenue Raymond Aron F-92165 Antony Cedex (FR)
Priority Data:
98/01065 30.01.1998 FR
60/077,026 06.03.1998 US
Title (EN) TRANSFECTING COMPOSITIONS SENSITIVE TO REDUCING CONDITIONS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR APPLICATIONS
(FR) COMPOSES TRANSFECTANTS SENSIBLES AUX CONDITIONS REDUCTRICES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, ET LEURS APPLICATIONS
Abstract: front page image
(EN)The invention concerns a novel agent for transferring nucleic acids into cells. Said agent is particularly characterised in that it comprises one or several disulphide bonds sensitive to reducing conditions. The invention also concerns compositions comprising such an agent for transferring $i(in vitro), $i(in vivo), or $i(ex vivo) nucleic acids of interest into different cell types.
(FR)La présente invention se rapporte à un nouvel agent pour le transfert d'acides nucléiques dans les cellules. Cet agent est plus particulièrement caractérisé en ce qu'il comporte un ou plusieurs ponts disulfure sensibles aux conditions réductrices. L'invention concerne également les compositions comprenant un tel agent, et ses utilisations pour le transfert $i(in vitro), $i(in vivo) ou $i(ex vivo) d'acides nucléiques d'intérêt dans différents types cellulaires.
Designated States: AL, AT, BA, BB, BG, BR, CA, CN, CU, CZ, EE, GD, GE, HU, ID, IL, IN, IS, JP, KP, KR, LC, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)