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Machine translation
1. (WO1999038514) CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/038514    International Application No.:    PCT/US1999/002165
Publication Date: 05.08.1999 International Filing Date: 01.02.1999
Chapter 2 Demand Filed:    27.08.1999    
IPC:
C07D 211/56 (2006.01), C07D 401/06 (2006.01), C07D 405/06 (2006.01), C07D 409/06 (2006.01), C07D 521/00 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
CALDWELL, Charles, G. [US/US]; (US) (For US Only).
FINKE, Paul, E. [US/US]; (US) (For US Only).
MACCOSS, Malcolm [GB/US]; (US) (For US Only).
MILLS, Sander, G. [US/US]; (US) (For US Only).
OATES, Bryan [US/US]; (US) (For US Only).
KIM, Dooseop [KR/US]; (US) (For US Only).
KOTHANDARAMAN, Shankaran [IN/US]; (US) (For US Only).
WANG, Liping [CN/US]; (US) (For US Only)
Inventors: CALDWELL, Charles, G.; (US).
FINKE, Paul, E.; (US).
MACCOSS, Malcolm; (US).
MILLS, Sander, G.; (US).
OATES, Bryan; (US).
KIM, Dooseop; (US).
KOTHANDARAMAN, Shankaran; (US).
WANG, Liping; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
60/073,446 02.02.1998 US
9810890.5 20.05.1998 GB
Title (EN) CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
(FR) AMINES CYCLIQUES UTILISEES EN TANT QUE MODULATEURS DE L'ACTIVITE DU RECEPTEUR DE CHEMOKINE
Abstract: front page image
(EN)The present invention is directed to cyclic amines of formula I (wherein R?1¿, R?2¿, R?3¿, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
(FR)Cette invention concerne des amines cycliques de formule (I). Dans la formule (I), R?1¿,R?2¿, R?3¿, m et n sont tels que dans le descriptif. Ces amines cycliques sont utiles en tant que modulateurs de l'activité du récepteur de chémokine, et de manière plus spécifique elles sont utiles en tant que modulateurs des récepteurs de chémokine CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3 et/ou CXCR-4.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GD, GE, HR, HU, ID, IL, IN, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, US, UZ, VN, YU.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)