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1. WO1999030817 - METHOD AND APPARATUS FOR CHEMICAL SYNTHESIS

Publication Number WO/1999/030817
Publication Date 24.06.1999
International Application No. PCT/GB1998/003761
International Filing Date 15.12.1998
Chapter 2 Demand Filed 06.07.1999
IPC
B01J 19/00 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
CPC
B01J 19/0046
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
B01J 2219/00286
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00279Features relating to reactor vessels
00281Individual reactor vessels
00286Reactor vessels with top and bottom openings
B01J 2219/00306
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00279Features relating to reactor vessels
00306Reactor vessels in a multiple arrangement
B01J 2219/00423
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00351Means for dispensing and evacuation of reagents
00423using filtration, e.g. through porous frits
B01J 2219/00454
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00452Means for the recovery of reactants or products
00454by chemical cleavage from the solid support
B01J 2219/00481
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00479Means for mixing reactants or products in the reaction vessels
00481by the use of moving stirrers within the reaction vessels
Applicants
  • KALIBRANT LIMITED [GB]/[GB] (AllExceptUS)
  • PALMER, Derek, Adeyemi [GB]/[GB] (UsOnly)
  • FRENCH, Martin, Thomas [GB]/[GB] (UsOnly)
Inventors
  • PALMER, Derek, Adeyemi
  • FRENCH, Martin, Thomas
Agents
  • KIRKHAM, Nicholas, Andrew
Priority Data
9726482.415.12.1997GB
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND APPARATUS FOR CHEMICAL SYNTHESIS
(FR) PROCEDE ET DISPOSITIF DE SYNTHESE CHIMIQUE
Abstract
(EN) The present invention provides a chemical synthesis apparatus comprising a plurality of reagent inputs (2) and a solid support input (1). Each input (1, 2) is connectable to a main fluid pathway via a respective switchable valve (3). The apparatus further includes a reaction chamber (4) fluidly connectable to the main fluid pathway by a respective switchable valve (3) downstream of the inputs (1, 2). The reaction chamber (4) further includes an outlet downstream of a barrier (5) arranged to prevent passage of said solid supports but allows passage of unbound molecules.
(FR) La présente invention décrit un dispositif de synthèse chimique comprenant une pluralité d'entrées (2) de réactifs et une entrée (1) de supports solides. Chaque entrée (1, 2) peut être reliée à un circuit principal de fluide au moyen d'une vanne commutable (3). Le dispositif comprend de plus une chambre de réaction (4) qui peut être reliée au réseau principal de fluide par une vanne commutable (3) située en aval des entrées (1, 2). La chambre de réaction (4) comprend de plus une sortie en aval d'une barrière (5), disposée de manière à empêcher le passage des supports solides, mais à laisser passer les molécules non liées.
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