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1. WO1999029251 - METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC AGENTS TO THE HEART

Publication Number WO/1999/029251
Publication Date 17.06.1999
International Application No. PCT/US1998/025848
International Filing Date 04.12.1998
IPC
A61B 17/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
A61B 18/24 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
18by applying electromagnetic radiation, e.g. microwaves
20using laser
22the beam being directed along or through a flexible conduit, e.g. an optical fibre; Hand-pieces therefor
24with a catheter
A61M 25/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
25Catheters; Hollow probes
A61M 29/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
29Dilators with or without means for introducing media, e.g. remedies
02Inflatable dilators; Dilators made of swellable materials
CPC
A61B 18/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
18by applying electromagnetic radiation, e.g. microwaves
20using laser
22the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or; hand-pieces therefor
24with a catheter
A61B 2017/00243
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
00234for minimally invasive surgery
00238Type of minimally invasive operation
00243cardiac
A61B 2017/00247
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
00234for minimally invasive surgery
00238Type of minimally invasive operation
00243cardiac
00247Making holes in the wall of the heart, e.g. laser Myocardial revascularization
A61B 2018/00232
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
00053Mechanical features of the instrument of device
00214Expandable means emitting energy, e.g. by elements carried thereon
0022Balloons
00232having an irregular shape
A61B 2018/00261
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
00053Mechanical features of the instrument of device
00214Expandable means emitting energy, e.g. by elements carried thereon
0022Balloons
0025Multiple balloons
00261arranged in a line
A61B 2018/00392
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
00315for treatment of particular body parts
00345Vascular system
00351Heart
00392Transmyocardial revascularisation
Applicants
  • HEARTPORT, INC. [US]/[US]
Inventors
  • STEVENS, John, H.
  • BREWER, Richard, B.
  • ROSENMAN, Daniel, C.
  • GIFFORD, Hanson, S.
Agents
  • GRAINGER, Jeffry, J.
Priority Data
08/986,91708.12.1997US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC AGENTS TO THE HEART
(FR) PROCEDE ET APPAREIL POUR LA LIBERATION D'AGENTS THERAPEUTIQUES DANS LE COEUR
Abstract
(EN) A method and system for delivering a therapeutic agent directly to the heart employing minimally invasive techniques and concepts. In particular, the delivery of vascular endothelial growth factors (VEGF) is performed endovascularly or endoscopically to a region of a patient's heart treated with transmyocardial revascularization (TMR). A system is provided for inducing cardioplegia arrest. An aortic occlusion device (10) has an inflatable balloon (11) which occludes the ascending aorta (12) when inflated.
(FR) Système et appareil pour libérer un agent thérapeutique directement dans le coeur, dans lesquels sont utilisés des techniques et des concepts avec effraction minimale. En particulier, la libération de facteurs de croissance de cellules endothéliales vasculaires (VGEF) est effectuée de manière endovasculaire ou endoscopique dans une région du coeur d'un patient traité par revascularisation transmyocardique. L'invention concerne un système pour induire une cardioplégie. Un dispositif (10) d'occlusion de l'aorte comporte un ballonnet (11) gonflable qui obstrue l'aorte ascendante (12) lorsqu'il est gonflé.
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