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1. WO1999018977 - READILY ABSORBABLE PHYTOSTEROL GLYCOSIDES TO TREAT HYPERCHOLESTEROLEMIA

Publication Number WO/1999/018977
Publication Date 22.04.1999
International Application No. PCT/US1998/021735
International Filing Date 14.10.1998
Chapter 2 Demand Filed 17.05.1999
IPC
A61K 9/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
CPC
A61K 31/704
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034attached to a carbocyclic compound, e.g. phloridzin
704attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
A61K 9/146
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
146with organic macromolecular compounds
Applicants
  • MEDICAL ISOTOPES INC. [US]/[US]
Inventors
  • STOHLER, Eric
Priority Data
60/062,96816.10.1997US
null13.10.1998US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) READILY ABSORBABLE PHYTOSTEROL GLYCOSIDES TO TREAT HYPERCHOLESTEROLEMIA
(FR) GLYCOSIDES DE PHYTOSTEROLS FACILEMENT ABSORBABLES TRAITANT L'HYPERCHOLESTEROLEMIE
Abstract
(EN)
A process of preparing sterol glycosides in a form that is easily absorbed through the digestive tract, and methods of treating cholesterolemia by administering a composition which includes at least one glycoside or glycoside ester of a steryl glycoside selected from a group consisting of $g(b)-sitosteryl-$g(b)-D-glycoside, stigmasteryl-$g(b)-D-glycoside and campasteryl-$g(b)-D-glycoside and saturated steryl glycosides corresponding thereto.
(FR)
L'invention porte sur un procédé de préparation de stérylglycosides sous une forme facilement assimilable par le tube digestif et sur des procédés de traitement de la cholestérolémie par administration d'une composition comportant au moins un glycoside ou un ester glycosidique d'un stérylglycoside choisi parmi le $g(b)-sitostéryl-$g(b)-D-glycoside, le stigmastéryl-$g(b)-D-glycoside, le campastéryl-$g(b)-D-glycoside, et des stérylglycosides saturés leur correspondant.
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