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1. WO1999017787 - USE OF A CHEMICALLY-STABILIZED CHLORITE SOLUTION FOR INHIBITING AN ANTIGEN-SPECIFIC IMMUNE RESPONSE

Publication Number WO/1999/017787
Publication Date 15.04.1999
International Application No. PCT/IB1998/001676
International Filing Date 06.10.1998
Chapter 2 Demand Filed 30.04.1999
IPC
A61K 33/40 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
40Peroxides
CPC
A61K 33/40
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
40Peroxides
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
Applicants
  • OXO CHEMIE AG [CH]/[CH]
Inventors
  • KUHNE, Frederich, W.
  • MCGRATH, Michael
  • ENGLEMAN, Edgar, G.
Agents
  • OLGEMÖLLER, Luitgard
Priority Data
60/060,95306.10.1997US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF A CHEMICALLY-STABILIZED CHLORITE SOLUTION FOR INHIBITING AN ANTIGEN-SPECIFIC IMMUNE RESPONSE
(FR) UTILISATION DE SOLUTION DE CHLORITE STABILISEE PAR VOIE CHIMIQUE AUX FINS DE L'INHIBITION D'UNE REPONSE IMMUNITAIRE SPECIFIQUE D'UN ANTIGENE
Abstract
(EN)
Methods of using a stabilized chlorite solution to inhibit antigen-specific immune responses are disclosed. The stabilized chlorite solution, when administered to a mammal in need thereof, can prevent the presentation of antigens by antigen presenting cells. The stabilized chlorite solution therefore is useful in treating, $i(inter alia), auto-immune diseases, treating diseases caused by an inappropriate immune response, treating lymphoproliferative disease and in inhibiting rejection in transplant patients.
(FR)
L'invention a trait à des techniques d'utilisation d'une solution de chlorite stabilisée aux fins de l'inhibition de réponses immunitaires spécifiques d'un antigène. Cette solution, une fois administrée à un mammifère la nécessitant, est capable d'empêcher la présentation d'antigènes par des cellules présentant l'antigène. Cette solution se révèle des plus utiles dans le traitement, entre autres, de maladies auto-immunes, de maladies dues à une réponse immunitaire inopportune et du syndrome lymphoprolifératif ainsi que pour inhiber le phénomène de rejet chez des patients ayant subi une transplantation.
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