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Machine translation
1. (WO1999013816) LIPOSOMAL CAMPTOTHECIN FORMULATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/013816    International Application No.:    PCT/US1998/019086
Publication Date: 25.03.1999 International Filing Date: 15.09.1998
Chapter 2 Demand Filed:    16.03.1999    
IPC:
A61K 9/127 (2006.01), A61K 31/4745 (2006.01), A61K 31/496 (2006.01)
Applicants: NEXSTAR PHARMACEUTICALS, INC. [US/US]; Suite 200 2860 Wilderness Place Boulder, CO 80301 (US) (For All Designated States Except US).
MOYNIHAN, Karen, Lewis [US/US]; (US) (For US Only).
EMERSON, David, Lloyd [US/US]; (US) (For US Only).
CHIANG, Su-Ming [US/US]; (US) (For US Only).
HU, Ning [CN/US]; (US) (For US Only)
Inventors: MOYNIHAN, Karen, Lewis; (US).
EMERSON, David, Lloyd; (US).
CHIANG, Su-Ming; (US).
HU, Ning; (US)
Agent: SWANSON, Barry, J.; Swanson & Bratschun, L.L.C. Suite 200 8400 East Prentice Avenue Englewood, CO 80111 (US)
Priority Data:
60/059,083 16.09.1997 US
Title (EN) LIPOSOMAL CAMPTOTHECIN FORMULATIONS
(FR) COMPOSITIONS A BASE DE LIPOSOMES RENFERMANT DE LA CAMPTOTHECINE
Abstract: front page image
(EN)Liposomal encapsulated camptothecin formulations are provided. The liposomes have improved pharmacokinetics, enhanced efficacy as anti-tumor agents and provide an increased therapeutic index as compared to the free drug and topotecan. The formulations include liposomes comprising at least one phospholipid and a camptothecin or analog thereof.
(FR)L'invention se rapporte à des compositions encapsulées à base de liposomes qui renfermant de la camptothécine. Les liposomes présentent des propriétés pharmacocinétiques et une efficacité améliorée en tant qu'agents anti-tumoraux et fournissent un indice thérapeutique accru par rapport à celui d'un médicament libre et du topotécan. Ces compositions renferment des liposomes contenant au moins un phospholipide et une campothécine ou un analogue de cette dernière.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)