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1. (WO1999012971) AMINO ACID SEQUENCES FOR THERAPEUTICAL AND PROPHYLACTIC APPLICATIONS TO DISEASES DUE TO $i(CLOSTRIDIUM DIFFICILE) TOXINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/012971    International Application No.:    PCT/EP1998/005759
Publication Date: 18.03.1999 International Filing Date: 10.09.1998
Chapter 2 Demand Filed:    25.03.1999    
IPC:
A61K 39/00 (2006.01), C07K 14/33 (2006.01), C07K 16/12 (2006.01)
Applicants: VON EICHEL-STREIBER, Christoph [DE/DE]; (DE).
MOOS, Michael [--/DE]; (DE) (For US Only)
Inventors: VON EICHEL-STREIBER, Christoph; (DE).
MOOS, Michael; (DE)
Priority Data:
197 39 685.2 10.09.1997 DE
Title (DE) AMINOSÄURESEQUENZEN ZUR THERAPIE UND PROPHYLAXE VON ERKRANKUNGEN DURCH $i(CLOSTRIDIUM DIFFICILE) TOXINE
(EN) AMINO ACID SEQUENCES FOR THERAPEUTICAL AND PROPHYLACTIC APPLICATIONS TO DISEASES DUE TO $i(CLOSTRIDIUM DIFFICILE) TOXINS
(FR) SEQUENCES D'ACIDES AMINES A USAGE THERAPEUTIQUE ET PROPHYLACTIQUE POUR LES MALADIES CAUSEES PAR DES TOXINES DE $i(CLOSTRIDIUM DIFFICILE)
Abstract: front page image
(DE)Es werden monoklonale Antikörper beschrieben, die Epitope der Ligandendomäne, der Translokationsdomäne oder der katalytischen Domäne des Enterotoxins (Toxin A) oder des Zytotoxins (Toxin B) von $i(Clostridium difficile) erkennen und neutralisieren können, sowie ihre Herstellung und ihre Verwendung zur Therapie and Prophylaxe der durch diese Toxine hervorgerufenen Erkrankungen.
(EN)The invention relates to monoclonal antibodies capable of recognizing and neutralizing epitopes from the ligand domain, the translocation domain or the catalytic domain for the enterotoxin (toxin A) and cytotoxin (toxin B) from $i(clostrodium difficile), as well as their production and therapeutical and prophylactic applications to diseases due to said toxins.
(FR)La présente invention porte sur des anticorps monoclonaux capables de reconnaître et de neutraliser les épitopes du domaine des ligants, du domaine de la translocation ou du domaine catalytique de l'entérotoxine (toxine A) ou de la cytotoxine (toxine B) de $i(clostridium difficile), ainsi que sur sa production et son application thérapeutique et prophylactique à l'égard des maladies causées par ces toxines.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)