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1. (WO1999012041) COMPOSITION AND METHODS USING GALECTIN-1
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/012041    International Application No.:    PCT/US1998/018371
Publication Date: 11.03.1999 International Filing Date: 03.09.1998
Chapter 2 Demand Filed:    22.03.1999    
IPC:
G01N 33/569 (2006.01), G01N 33/68 (2006.01)
Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA [US/US]; 1000 Asp Avenue Norman, OK 73019 (US)
Inventors: CUMMINGS, Richard, D.; (US).
CHO, Moon-Jae; (US)
Agent: PALMER, John; Ladas & Parry Suite 2100 5670 Wilshire Boulevard Los Angeles, CA 90036-5679 (US)
Priority Data:
08/924,289 05.09.1997 US
08/929,291 05.09.1997 US
Title (EN) COMPOSITION AND METHODS USING GALECTIN-1
(FR) COMPOSITION ET METHODES UTILISANT LA GALECTINE-1
Abstract: front page image
(EN)Methods for treating and modulating an inflammatory response using compositions containing a primarily monomeric or primarily dimeric form of galectin-1. The dimeric form stimulates apoptosis of activated neutrophils while the monomeric form inhibits apoptosis of activated neutrophils. Methods of screening for compounds which have galectin-1-like functions are also identified.
(FR)L'invention concerne des méthodes permettant de traiter et de moduler une réaction inflammatoire à l'aide de compositions contenant une forme principalement monomère ou principalement dimère de galectine-1. La forme dimère stimule l'apoptose des neutrophiles activés tandis que la forme monomère inhibe leur apoptose. Cette invention se rapporte également à des méthodes d'analyse de composés dotés de fonctions semblables à celles de la galectine-1.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)