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1. (WO1999011606) INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/011606    International Application No.:    PCT/US1998/017327
Publication Date: 11.03.1999 International Filing Date: 24.08.1998
Chapter 2 Demand Filed:    23.03.1999    
IPC:
A61K 38/00 (2006.01), C07C 235/74 (2006.01), C07C 235/80 (2006.01), C07C 237/52 (2006.01), C07C 271/02 (2006.01), C07C 271/22 (2006.01), C07C 275/24 (2006.01), C07C 305/24 (2006.01), C07C 311/06 (2006.01), C07C 311/13 (2006.01), C07C 311/37 (2006.01), C07C 317/50 (2006.01), C07C 323/59 (2006.01), C07D 295/13 (2006.01), C07D 295/215 (2006.01), C07D 521/00 (2006.01), C07K 5/06 (2006.01), C07K 5/065 (2006.01), C07K 5/068 (2006.01), C07K 5/072 (2006.01), C07K 5/078 (2006.01)
Applicants: PHARMACIA & UPJOHN COMPANY [US/US]; 301 Henrietta Street Kalamazoo, MI 49001 (US) (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW only).
LARSEN, Scott, D. [US/US]; (US) (For US Only).
MAY, Paul, D. [US/US]; (US) (For US Only).
BLEASDALE, John [GB/US]; (US) (For US Only).
LILJEBRIS, Charlotta [SE/SE]; (SE) (For US Only).
SCHOSTAREZ, Heinrich, Josef [US/US]; (US) (For US Only).
BARF, Tjeerd [NL/SE]; (SE) (For US Only)
Inventors: LARSEN, Scott, D.; (US).
MAY, Paul, D.; (US).
BLEASDALE, John; (US).
LILJEBRIS, Charlotta; (SE).
SCHOSTAREZ, Heinrich, Josef; (US).
BARF, Tjeerd; (SE)
Agent: BAILEY, John, W.; Birch, Stewart, Kolasch & Birch P.O. Box 747 Falls Church, VA 22020-0747 (US)
Priority Data:
60/057,730 28.08.1997 US
Title (EN) INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE
(FR) INHIBITEURS DE LA PROTEINE TYROSINE PHOSPHATASE
Abstract: front page image
(EN)The present invention comprises small molecular weight, non-peptidic inhibitors of formula (I) and (II) of Protein Tyrosine Phosphatase 1 (PTP1) which are useful for the treatment and/or prevention of Non-Insulin Dependent Diabetes Mellitus (NIDDM).
(FR)Cette invention a trait à des inhibiteurs non peptidiques, de faible poids moléculaire, correspondant aux formules I et II, de la protéine tyrosine phosphatase utilisés pour le traitement et la prévention du diabète sucré non-insulino-dépendant.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)