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1. (WO1999010529) METHODS FOR ANALYZING LTC4 SYNTHASE POLYMORPHISMS AND DIAGNOSTIC USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/010529    International Application No.:    PCT/GB1998/002468
Publication Date: 04.03.1999 International Filing Date: 18.08.1998
Chapter 2 Demand Filed:    24.02.1999    
IPC:
C12Q 1/68 (2006.01)
Applicants: ZENECA LIMITED [GB/GB]; 15 Stanhope Gate London W1Y 6LN (GB) (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW only).
MORTEN, John, Edward, Norris [GB/GB]; (GB) (For US Only)
Inventors: MORTEN, John, Edward, Norris; (GB)
Agent: GILES, Allen, Frank; Zeneca Pharmaceuticals Intellectual Property Dept. Mereside, Alderley Park Macclesfield Cheshire SK10 4TG (GB)
Priority Data:
9717766.1 22.08.1997 GB
Title (EN) METHODS FOR ANALYZING LTC4 SYNTHASE POLYMORPHISMS AND DIAGNOSTIC USE
(FR) PROCEDES D'ANALYSE DES POLYMORPHISMES DE SYNTHESE DU LTC4 ET UTILISATION DIAGNOSTIQUE
Abstract: front page image
(EN)This invention relates to single nucleotide polymorphisms in the LTC¿4? synthase gene, EMBL accession no. U50136, particularly at one or more of positions 375, 815, 1003, 2169 and 2742. The invention also relates to methods and materials for analysing allelic variation in the LTC¿4? synthase gene, and to the use of LTC¿4? synthase polymorphism in the diagnosis and treatment of leukotriene mediated diseases such as asthma and allergic rhinitis.
(FR)La présente invention à trait à des polymorphismes nucléotidiques simples dans le gène de synthèse du LTC¿4?, acquisition n° U50136 de l'EMBL, et particulièrement dans une ou plusieurs des positions 375, 815, 1003, 2169 et 2742 . L'invention concerne également des procédés et des substances permettant d'analyser la variation allélique dans le gène de synthèse du LTC¿4?, et l'utilisation du polymorphisme de synthèse du LTC¿4? dans le diagnostic et le traitement des maladies induites par la leucotriène, telles que l'asthme et les rhinites allergiques.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)