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1. (WO1999008997) NOVEL LIPOPOLYAMINES, AND THE PREPARATION AND USE THEREOF

Pub. No.:    WO/1999/008997    International Application No.:    PCT/EP1998/005156
Publication Date: Feb 25, 1999 International Filing Date: Aug 13, 1998
IPC: A61K 9/127
A61K 47/48
A61K 48/00
C07C 211/14
C07C 217/42
C07C 219/06
C07C 229/16
C07C 237/10
C12N 15/87
Applicants: BIONTEX LABORATORIES GMBH
KLÖSEL, Roland
KÖNIG, Stephan
Inventors: KLÖSEL, Roland
KÖNIG, Stephan
Title: NOVEL LIPOPOLYAMINES, AND THE PREPARATION AND USE THEREOF
Abstract:
The invention relates to novel lipopolyamines (including their salts), characterised by a symmetrical, highly flexible lipophilic component with a buffering capacity at physiological pH, and to their use for funnelling biologically active materials such as DNA, RNA, ribozymes, antisense DNA, peptides and proteins into eukaryotic cells in vivo or in vitro.