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1. (WO1999008524) METHODS FOR PREVENTING HEADACHES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/008524    International Application No.:    PCT/US1998/016996
Publication Date: 25.02.1999 International Filing Date: 17.08.1998
Chapter 2 Demand Filed:    22.02.1999    
IPC:
A61K 31/4535 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center Indianapolis, IN 46285 (US) (AL, AM, AU, AZ, BA, BB, BF, BG, BJ, BR, BY, CA, CF, CG, CI, CM, CN, CU, CZ, EE, GA, GE, GH, GM, GN, GW, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LV, MD, MG, MK, ML, MN, MR, MW, MX, NE, NO, NZ, PL, RO, RU, SD, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW only).
LAKSHMANAN, Mark, Chandrakant [US/US]; (US) (For US Only)
Inventors: LAKSHMANAN, Mark, Chandrakant; (US)
Agent: SALES, James, J.; Eli Lilly and Company Lilly Corporate Center Indianapolis, IN 46285 (US)
Priority Data:
60/056,747 20.08.1997 US
Title (EN) METHODS FOR PREVENTING HEADACHES
(FR) PROCEDES DE PREVENTION DES MAUX DE TETE
Abstract: front page image
(EN)A method of preventig headhache in a human which comprises the administration to a human in need thereof of an effective amount of a compound of formula (I) wherein R?1¿ and R?3¿ are, independently, -H, -CH¿3?, -CO(C¿1?-C¿6? alkyl), or -COAr, where Ar is optionally substituted phenyl; R?3¿ is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof.
(FR)L'invention concerne un procédé permettant de prévenir les maux de tête chez un sujet humain. Ce procédé consiste à administrer au sujet une quantité efficace d'un composé présentant la formule (I). Dans cette dernière, R?1¿ et R?3¿ sont, indépendamment, -H, -CH¿3?, -CO(alkyle C¿1?-C¿6?), ou -COAr, où Ar est éventuellement du phényle substitué; R?3¿ est sélectionné dans le groupe se composant de pyrrolidine, pipéridine, et héxaméthylèneimino; ou un sel pharmaceutiquement acceptable ou un solvate de ce dernier.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, RO, RU, SD, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)