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1. (WO1999007707) 8-SUBSTITUTED-9H-1,3-DIOXOLO/4,5-h//2,3/BENZODIAZEPINE DERIVATIVES, AS AMPA/KAINATE RECEPTOR INHIBITORS
Latest bibliographic data on file with the International Bureau   
Pub. No.: WO/1999/007707 International Application No.: PCT/HU1998/000075
Publication Date: 18.02.1999 International Filing Date: 07.08.1998
Chapter 2 Demand Filed: 02.03.1999
IPC:
C07D 491/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
RÁTKAI, Zoltán [HU/HU]; HU (UsOnly)
BARKÓCZY, József [HU/HU]; HU (UsOnly)
SCHNEIDER, Géza [HU/HU]; HU (UsOnly)
CSELENYÁK, Judit [HU/HU]; HU (UsOnly)
SIMIG, Gyula [HU/HU]; HU (UsOnly)
BALÁZS, László [HU/HU]; HU (UsOnly)
DOMÁN, Imre [HU/HU]; HU (UsOnly)
GREFF, Zoltán [HU/HU]; HU (UsOnly)
KÓTAY NAGY, Péter [HU/HU]; HU (UsOnly)
SERES, Péter [HU/HU]; HU (UsOnly)
SZABÓ, Géza [HU/HU]; HU (UsOnly)
GACSÁLYI, István [HU/HU]; HU (UsOnly)
GIGLER, Gábor [HU/HU]; HU (UsOnly)
GYERTYÁN, István [HU/HU]; HU (UsOnly)
LÉVAY, György [HU/HU]; HU (UsOnly)
KOVÁCS, Attila [HU/HU]; HU (UsOnly)
SIMÓ, Annamária [HU/HU]; HU (UsOnly)
SZABADOS, Tamás [HU/HU]; HU (UsOnly)
EGYED, András [HU/HU]; HU (UsOnly)
VÉGH, Miklós [HU/HU]; HU (UsOnly)
TIHANYI, Károly [HU/HU]; HU (UsOnly)
EGIS GYÓGYSZERGYÁR RT. [HU/HU]; Keresztúri út 30-38 H-1106 Budapest, HU (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
Inventors:
RÁTKAI, Zoltán; HU
BARKÓCZY, József; HU
SCHNEIDER, Géza; HU
CSELENYÁK, Judit; HU
SIMIG, Gyula; HU
BALÁZS, László; HU
DOMÁN, Imre; HU
GREFF, Zoltán; HU
KÓTAY NAGY, Péter; HU
SERES, Péter; HU
SZABÓ, Géza; HU
GACSÁLYI, István; HU
GIGLER, Gábor; HU
GYERTYÁN, István; HU
LÉVAY, György; HU
KOVÁCS, Attila; HU
SIMÓ, Annamária; HU
SZABADOS, Tamás; HU
EGYED, András; HU
VÉGH, Miklós; HU
TIHANYI, Károly; HU
Agent:
ADVOPATENT OFFICE OF PATENT AND TRADEMARK ATTORNEYS; P.O. Box 11 H-1251 Budapest, HU
Priority Data:
P 97 0138012.08.1997HU
P 97 0138112.08.1997HU
Title (EN) 8-SUBSTITUTED-9H-1,3-DIOXOLO/4,5-h//2,3/BENZODIAZEPINE DERIVATIVES, AS AMPA/KAINATE RECEPTOR INHIBITORS
(FR) DERIVES DE 9H-1,3-DIOXOLO/4,5-h//2,3/BENZODIAZEPINE SUBSTITUEE EN HUIT UTILISES COMME INHIBITEURS DES RECEPTEURS D'AMPA/KAINATE
Abstract:
(EN) The invention refers to novel 8-substituted-9H-1,3-dioxolo/4,5-h//2,3/benzodiazepine derivatives of formula (I), a process for preparing these compounds and to pharmaceutical compositions containing these active substances. Compounds (I) inhibit Ampa/Kainate receptors.
(FR) L'invention concerne de nouveaux dérivés de 9H-1,3-dioxolo/4,5-h//2,3/benzodiazépine substituée en huit de formule (I), un procédé pour préparer ces composés, et des compositions pharmaceutiques contenant ces substances actives. Les composés (I) inhibent les récepteurs d'Ampa/Kainate.
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Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)