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1. (WO1999007410) PHARMACEUTICAL COMPOSITION WITH NEUROTROPHIC-LIKE BIOLOGICAL ACTIVITY

Pub. No.:    WO/1999/007410    International Application No.:    PCT/CA1998/000749
Publication Date: Fri Feb 19 00:59:59 CET 1999 International Filing Date: Thu Aug 06 01:59:59 CEST 1998
IPC: A61K 38/18
A61K 38/19
C07K 16/28
Applicants: MCGILL UNIVERSITY
SARAGOVI, H., Uri
MALIARTCHOUK, Sergei
Inventors: SARAGOVI, H., Uri
MALIARTCHOUK, Sergei
Title: PHARMACEUTICAL COMPOSITION WITH NEUROTROPHIC-LIKE BIOLOGICAL ACTIVITY
Abstract:
The present invention relates to a pharmaceutical composition having a neurotrophic-like biological activity which comprises a first compound which binds to and/or activates at least one trk receptor, and a second component which binds to and/or activates p75 receptor, in association with a pharmaceutically acceptable carrier. The neurotrophic-like biological activity may be that of NGF. The trk receptor may be selected from the group consisting of trkA, trkB and trkC.