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1. WO1999007375 - USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING AGGRESSIVE BEHAVIOUR DISORDERS

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Publication Number WO/1999/007375
Publication Date 18.02.1999
International Application No. PCT/EP1998/004933
International Filing Date 31.07.1998
Chapter 2 Demand Filed 21.01.1999
IPC
A61K 31/439 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
439the ring forming part of a bridged ring system, e.g. quinuclidine
CPC
A61K 31/439
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
439the ring forming part of a bridged ring system, e.g. quinuclidine
A61K 31/5375
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
53751,4-Oxazines, e.g. morpholine
Applicants
  • MERCK SHARP & DOHME LIMITED [GB]/[GB] (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
  • RUPNIAK, Nadia, Melanie [GB]/[GB] (UsOnly)
Inventors
  • RUPNIAK, Nadia, Melanie
Agents
  • HISCOCK, Ian
Priority Data
9716457.804.08.1997GB
9812615.411.06.1998GB
PCT/EP97/0668925.11.1997EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING AGGRESSIVE BEHAVIOUR DISORDERS
(FR) UTILISATION D'ANTAGONISTES DU RECEPTEUR NK-1 POUR LE TRAITEMENT DE TROUBLES DU COMPORTEMENT AGRESSIFS
Abstract
(EN) The present invention provides the use of an NK-1 receptor antagonist, and optionally an antipsychotic agent, for the manufacture of a medicament for the treatment or prevention of aggressive behaviour, methods of treatment using such an NK-1 receptor antagonist and pharmaceutical compositions and products comprising it.
(FR) La présente invention concerne l'utilisation d'un antagoniste du récepteur NK-1, pénétrant dans le SNC, à action prolongée, oralement actif, et éventuellement d'un agent antipsychotique, pour produire un médicament destiné au traitement ou à la prévention d'un comportement agressif, des méthodes de traitement utilisant cet antagoniste du récepteur NK-1, ainsi que des compositions et des produits pharmaceutiques le renfermant.
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