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1. (WO1999007375) USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING AGGRESSIVE BEHAVIOUR DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1999/007375 International Application No.: PCT/EP1998/004933
Publication Date: 18.02.1999 International Filing Date: 31.07.1998
Chapter 2 Demand Filed: 21.01.1999
IPC:
A61K 31/439 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
439
the ring forming part of a bridged ring system, e.g. quinuclidine
Applicants: RUPNIAK, Nadia, Melanie[GB/GB]; GB (UsOnly)
MERCK SHARP & DOHME LIMITED[GB/GB]; Hertford Road Hoddesdon Hertfordshire EN11 9BU, GB (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
Inventors: RUPNIAK, Nadia, Melanie; GB
Agent: HISCOCK, Ian; Merck & Co., Inc. European Patent Dept. Terlings Park Eastwick Road, Harlow Essex CM20 2QR, GB
Priority Data:
9716457.804.08.1997GB
9812615.411.06.1998GB
PCT/EP97/0668925.11.1997EP
Title (EN) USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING AGGRESSIVE BEHAVIOUR DISORDERS
(FR) UTILISATION D'ANTAGONISTES DU RECEPTEUR NK-1 POUR LE TRAITEMENT DE TROUBLES DU COMPORTEMENT AGRESSIFS
Abstract:
(EN) The present invention provides the use of an NK-1 receptor antagonist, and optionally an antipsychotic agent, for the manufacture of a medicament for the treatment or prevention of aggressive behaviour, methods of treatment using such an NK-1 receptor antagonist and pharmaceutical compositions and products comprising it.
(FR) La présente invention concerne l'utilisation d'un antagoniste du récepteur NK-1, pénétrant dans le SNC, à action prolongée, oralement actif, et éventuellement d'un agent antipsychotique, pour produire un médicament destiné au traitement ou à la prévention d'un comportement agressif, des méthodes de traitement utilisant cet antagoniste du récepteur NK-1, ainsi que des compositions et des produits pharmaceutiques le renfermant.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)