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1. (WO1999007367) ASYMMETRIC CONJUGATE ADDITION REACTION
PCT Biblio. Data
Description
Claims
National Phase
Notices
Documents
Latest bibliographic data on file with the International Bureau
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Pub. No.:
WO/1999/007367
International Application No.:
PCT/US1998/016251
Publication Date:
18.02.1999
International Filing Date:
04.08.1998
Chapter 2 Demand Filed:
17.02.1999
IPC:
C07D 405/04
(2006.01) ,
C07D 405/06
(2006.01) ,
C07D 413/14
(2006.01)
C
CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
C
CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C
CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
14
containing three or more hetero rings
Applicants:
DEVINE, Paul, N.
[US/US]; US (UsOnly)
HEID, Richard, M., Jr.
[US/US]; US (UsOnly)
TILLYER, Richard, D.
[GB/US]; US (UsOnly)
TSCHAEN, David, M.
[US/US]; US (UsOnly)
MERCK & CO., INC.
[US/US]; 126 East Lincoln Avenue Rahway, NJ 07065, US (AllExceptUS)
Inventors:
DEVINE, Paul, N.
; US
HEID, Richard, M., Jr.
; US
TILLYER, Richard, D.
; US
TSCHAEN, David, M.
; US
Common
Representative:
MERCK & CO., INC.
; 126 East Lincoln Avenue Rahway, NJ 07065, US
Priority Data:
60/055,259
08.08.1997
US
60/087,039
28.05.1998
US
9810550.5
15.05.1998
GB
Title
(EN)
ASYMMETRIC CONJUGATE ADDITION REACTION
(FR)
REACTION D'ADDITION CONJUGUEE ASYMETRIQUE
Abstract:
(EN)
This invention relates to a key intermediate in the synthesis of an endothelin antagonist the synthesis of this key intermediate via an asymmetric conjugate addition reaction.
(FR)
L'invention concerne un intermédiaire clé dans la synthèse d'un antagoniste d'endothéline, ainsi que la synthèse de cet intermédiaire clé par une réaction d'addition conjuguée asymétrique.
Designated States:
AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CU, CZ, EE, GE, HR, HU, ID, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, SL, TJ, TM, TR, TT, UA, US, UZ, VN, YU
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language:
English (
EN
)
Filing Language:
English (
EN
)