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Machine translation
1. (WO1999007361) METHODS FOR CONTROLLING GRAM NEGATIVE BACTERIA IN MAMMALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/007361    International Application No.:    PCT/US1998/016299
Publication Date: 18.02.1999 International Filing Date: 05.08.1998
Chapter 2 Demand Filed:    24.02.1999    
IPC:
A61K 31/35 (2006.01)
Applicants: MILLENNIUM PHARMACEUTICALS, INC. [US/US]; 238 Main Street Cambridge, MA 02142-1017 (US)
Inventors: BERKOWITZ, Barry; (US).
SACHS, George; (US).
BLACKBURN, Chris; (US)
Agent: ROTHENBERGER, Scott, D.; Lahive & Cockfield, LLP 28 State Street Boston, MA 02109 (US)
Priority Data:
08/905,985 05.08.1997 US
Title (EN) METHODS FOR CONTROLLING GRAM NEGATIVE BACTERIA IN MAMMALS
(FR) PROCEDE DE LUTTE CONTRE LES BACTERIES GRAM NEGATIF CHEZ LES MAMMIFERES
Abstract: front page image
(EN)Methods for controlling growth of gram negative bacteria, such as $i(Helicobacter pylori), which are agents associated with disorders of the gastrointestinal tract of a mammal are described. They include administering a therapeutically effective amount of a polyether ionophore antibiotic to a mammal, such that growth of gram negative bacteria which are agents associated with disorders of the gastrointestinal tract of a mammal is controlled. Packaged pharmaceutical compositions for controlling gram negative bacteria are also described. The packaged compositions include a container holding a therapeutically effective amount of a pharmaceutical composition for controlling gram negative bacteria which are agents associated with disorders of the gastrointestinal tract of a mammal and instructions for using the pharmaceutical composition for control of the gram negative bacteria, such that growth of gram negative bacteria which are agents associated with disorders of the gastrointestinal tract of a mammal is controlled. The pharmaceutical composition includes at least one polyether ionophore antibiotic or a bicyclic spiroether.
(FR)L'invention concerne des procédés de lutte contre la croissance de bactéries Gram négatif, comme $i(Helicobacter pylori), lesquelles sont des agents associés à des troubles du tractus gastro-intestinal chez un mammifère. Ces procédés consistent à administrer à un mammifère une dose efficace sur le plan thérapeutique d'un antibiotique ionophore à base de polyéther, de façon à juguler la croissance des bactéries Gram négatif qui sont des agents associés aux troubles du tractus gastro-intestinal. L'invention concerne également des compositions pharmaceutiques conditionnées, comprenant un contenant renfermant une dose efficace sur le plan thérapeutique d'une composition pharmaceutique servant à lutter contre des bactéries Gram négatif, associées aux troubles du tractus gastro-intestinal chez un mammifère, ainsi que des instructions d'utilisation de cette composition pharmaceutique de lutte contre ces bactéries, de manière à juguler la croissance de celles-ci. Cette composition pharmaceutique comprend au moins un antibiotique ionophore à base de polyéther ou un spiroéther bicyclique.
Designated States: AU, CA, JP.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)