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Machine translation
1. (WO1999006831) BREAST CANCER RESISTANCE GENES, METHODS FOR THEIR DETECTION AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/006831    International Application No.:    PCT/EP1998/004754
Publication Date: 11.02.1999 International Filing Date: 29.07.1998
Chapter 2 Demand Filed:    23.02.1999    
IPC:
G01N 33/574 (2006.01)
Applicants: DORSSERS, Lambert, C., J. [NL/NL]; (NL)
Inventors: DORSSERS, Lambert, C., J.; (NL)
Agent: BRASNETT, Adrian, H.; Mewburn Ellis, York House, 23 Kingsway, London WC2B 6HP (GB)
Priority Data:
60/054,101 29.07.1997 US
Title (EN) BREAST CANCER RESISTANCE GENES, METHODS FOR THEIR DETECTION AND USES THEREOF
(FR) GENES DE RESISTANCE AUX CARCINOMES MAMMAIRES, PROCEDE DE DETECTION ET D'UTILISATION DE CES GENES R
Abstract: front page image
(EN)The present invention relates to the finding of genes associated with the development of estrogen independent malignant cell growth, particularly of breast cancer cells. The invention provides assay methods for the diagnosis or prognosis of malignant cell growth, which method comprises measuring the expression of one or more of the $i(BCAR1), $i(BCAR2) or $i(BCAR3) genes in a biological sample from a patient. Measurement may be by immunological techniques or by hybridisation with nucleic acids, utilising novel sequences and antibodies of the invention.
(FR)Cette invention concerne la découverte de gènes associés à la croissance de cellules malignes indépendantes des oestrogènes, plus particulièrement de cellules de carcinomes mammaires. L'invention concerne des procédés de dosage permettant d'effectuer le diagnostic ou le prognostic de la croissance de cellules malignes, ce procédé consistant à mesurer l'expression d'un ou de plusieurs gènes BCAR1, BCAR2 ou BCAR3 dans un prélèvement biologique d'un patient. La mesure peut être effectuée au moyen de techniques immunologiques ou par hybridation avec des acides nucléiques, dans lesquelles on utilise les nouvelles séquences et les nouveaux anticorps de cette invention.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)