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1. (WO1999006547) PRODUCTS OF GENE AND PROTEIN THERAPY OF CYSTIC FIBROSIS AND INDUCERS OF A GLUTATHIONES-S-TRANSFERASE

Pub. No.:    WO/1999/006547    International Application No.:    PCT/FR1998/001704
Publication Date: Fri Feb 12 00:59:59 CET 1999 International Filing Date: Fri Jul 31 01:59:59 CEST 1998
IPC: A61K 38/00
A61K 48/00
C07K 14/47
C12N 9/10
Applicants: ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
LENOIR, Gérard
BARTHE, Jöel
LALLEMAND, Jean-Yves
STOVEN, Véronique
ANNEREAU, Jean-Philippe
Inventors: LENOIR, Gérard
BARTHE, Jöel
LALLEMAND, Jean-Yves
STOVEN, Véronique
ANNEREAU, Jean-Philippe
Title: PRODUCTS OF GENE AND PROTEIN THERAPY OF CYSTIC FIBROSIS AND INDUCERS OF A GLUTATHIONES-S-TRANSFERASE
Abstract:
The invention concerns a DNA molecule containing a DNA sequence whereof the expression product has a common peptide sequence with part of that of CFTR, in particular the one extending from the 430th to the 660th residue of the latter and having a glutathione carrier function. Said DNA molecule is useful for constructing vectors useful in gene therapy for treating cystic fibrosis.