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1. (WO1999006538) THERMOCOCCUS BAROSII DNA POLYMERASE MUTANTS

Pub. No.:    WO/1999/006538    International Application No.:    PCT/US1998/016170
Publication Date: Fri Feb 12 00:59:59 CET 1999 International Filing Date: Tue Aug 04 01:59:59 CEST 1998
IPC: C12N 9/12
C12Q 1/68
Applicants: AMERSHAM PHARMACIA BIOTECH INC.
Inventors: RIEDL, William, A.
FLY, Susan, J.
KABOORD, Barbara, F.
NYE, Steven, H.
TING, Eve, Y.
Title: THERMOCOCCUS BAROSII DNA POLYMERASE MUTANTS
Abstract:
A Thermococcus barosii DNA polymerase with reduced 3'-5' exonuclease activity is disclosed. Additionally disclosed is a Thermococcus barosii DNA polymerase with increased ability to incorporate ribonucleotides and dideoxynucleotides.