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1. (WO1999006445) GROWTH DIFFERENTIATION FACTOR-15
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1999/006445 International Application No.: PCT/US1998/015455
Publication Date: 11.02.1999 International Filing Date: 24.07.1998
Chapter 2 Demand Filed: 25.02.1999
IPC:
A61K 38/00 (2006.01) ,A61K 48/00 (2006.01) ,C07K 14/475 (2006.01) ,G01N 33/574 (2006.01) ,G01N 33/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
Applicants:
LEE, Se-Jin [US/US]; US (UsOnly)
HUYNH, Thanh, V. [US/US]; US (UsOnly)
SEBALD, Suzanne [US/US]; US (UsOnly)
RANKIN, Christopher [US/US]; US (UsOnly)
HSIAO, Edward [US/US]; US (UsOnly)
THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE [US/US]; 720 Rutland Avenue Baltimore, MD 21205, US (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
Inventors:
LEE, Se-Jin; US
HUYNH, Thanh, V.; US
SEBALD, Suzanne; US
RANKIN, Christopher; US
HSIAO, Edward; US
Agent:
HAILE, Lisa, A.; Fish & Richardson P.C. Suite 1400 4225 Executive Square La Jolla, CA 92037, US
Priority Data:
60/054,40031.07.1997US
Title (EN) GROWTH DIFFERENTIATION FACTOR-15
(FR) FACTEUR DE DIFFERENCIATION EN COURS DE CROISSANCE 15
Abstract:
(EN) Growth differentiation factor-15 (GDF-15) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-15 polypeptide and polynucleotide sequences.
(FR) La présente invention concerne un facteur de différenciation en cours de croissance 15 (GDF-15) ainsi que sa séquence de polynucléotide et sa séquence d'acide aminé. La présente invention concerne également des procédés diagnostiques et thérapeutiques faisant appel au polypeptide GDF-15 et aux séquences de polynucléotides correspondantes.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)