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1. (WO1999006426) NOVEL MOLECULES OF THE TANGO-77 RELATED PROTEIN FAMILY AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1999/006426 International Application No.: PCT/US1998/016102
Publication Date: 11.02.1999 International Filing Date: 03.08.1998
Chapter 2 Demand Filed: 04.03.1999
IPC:
A61K 38/00 (2006.01) ,C07K 14/52 (2006.01) ,C12N 15/11 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
52
Cytokines; Lymphokines; Interferons
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
Applicants:
MILLENNIUM BIOTHERAPEUTICS, INC. [US/US]; 620 Memorial Drive Cambridge, MA 02142, US
Inventors:
PAN, Yang; US
Agent:
MEIKLEJOHN, Anita, L.; Fish & Richardson P.C. 225 Franklin Street Boston, MA 02110-2804, US
Priority Data:
60/054,64604.08.1997US
60/091,65002.07.1998US
Title (EN) NOVEL MOLECULES OF THE TANGO-77 RELATED PROTEIN FAMILY AND USES THEREOF
(FR) NOUVELLES MOLECULES DE LA FAMILLE DES PROTEINES DE TYPE TANGO-77 ET UTILISATIONS DE CES MOLECULES
Abstract:
(EN) Novel Tango-77 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Tango-77 proteins, the invention further provides isolated Tango-77 fusion proteins, antigenic peptides and anti-Tango-77 antibodies. The invention also provides Tango-77 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Tango-77 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
(FR) L'invention a trait à de nouvelles molécules d'acides nucléiques, protéines et à de nouveaux polypeptides de type Tango-77. Outre les protéines Tango-77 complètes isolées, l'invention concerne encore des protéines hybrides Tango-77 isolées, des peptides antigéniques et des anticorps dirigés contre la Tango-77. L'invention traite également de molécules d'acides nucléiques de type Tango-77, de vecteurs d'expression recombinants renfermant une molécule d'acides nucléiques selon l'invention, des cellules hôtes dans lesquelles lesdits vecteurs d'expression ont été introduits ainsi que des animaux transgéniques non humains dans lesquels un gène de Tango-77 a été introduit ou lysé. L'invention concerne enfin des procédés thérapeutiques, diagnostiques et de ciblage utilisant des compositions selon l'invention.
Designated States: AU, CA, JP
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)