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Machine translation
1. (WO1999006364) PROCESS FOR THE PURIFICATION OR ISOLATION OF (2S, 3R)-1-HALO-2-HYDROXY-3-(PROTECTED AMINO)-4-PHENYLTHIOBUTANES OR OPTICAL ANTIPODES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1999/006364    International Application No.:    PCT/JP1998/003375
Publication Date: 11.02.1999 International Filing Date: 29.07.1998
IPC:
C07C 319/28 (2006.01), C07C 323/25 (2006.01)
Applicants: KANEKA CORPORATION [JP/JP]; 2-4, Nakanoshima 3-chome, Kita-ku, Osaka-shi, Osaka 530-8288 (JP) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, MX, NL, PT, SE only).
UEDA, Yasuyoshi [JP/JP]; (JP) (For US Only).
MAEHARA, Katsuji [JP/JP]; (JP) (For US Only).
SUGAWA, Tadashi [JP/JP]; (JP) (For US Only).
MURAO, Hiroshi [JP/JP]; (JP) (For US Only).
NISHIYAMA, Akira [JP/JP]; (JP) (For US Only).
MANABE, Hajime [JP/JP]; (JP) (For US Only)
Inventors: UEDA, Yasuyoshi; (JP).
MAEHARA, Katsuji; (JP).
SUGAWA, Tadashi; (JP).
MURAO, Hiroshi; (JP).
NISHIYAMA, Akira; (JP).
MANABE, Hajime; (JP)
Agent: YASUTOMI, Yasuo; Recruit Shin Osaka Building 4F, 14-22, Nishinakajima 5-chome, Yodogawa-ku, Osaka-shi, Osaka 532-0011 (JP)
Priority Data:
9/219104 29.07.1997 JP
10/139310 21.05.1998 JP
Title (EN) PROCESS FOR THE PURIFICATION OR ISOLATION OF (2S, 3R)-1-HALO-2-HYDROXY-3-(PROTECTED AMINO)-4-PHENYLTHIOBUTANES OR OPTICAL ANTIPODES THEREOF
(FR) PROCEDE DE PURIFICATION OU D'ISOLATION DE (2S, 3R)-1-HALO-2-HYDROXY-3-(AMINO PROTEGE)-4-PHENYLTHIOBUTANES OU DE LEURS ANTIPODES OPTIQUES
Abstract: front page image
(EN)A process for the purification or isolation of (2S, 3R)-1-halo-2-hydroxy-3-(protected amino)-4-phenylthiobutanes of general formula (1) or optical antipodes thereof, which comprises ridding a compound of general formula (1) contaminated with impurities or an optical antipode thereof contaminated similarly by the use of an aromatic hydrocarbon solvent to thereby obtain the compound or the antipode as a crystal. In said formula, X is halogeno; and P?1¿ and P?2¿ are each independently hydrogen or an amino-protecting group, or alternatively P?1¿ and P?2¿ may be united to form an amino-protecting group.
(FR)L'invention porte sur un procédé de purification ou d'isolation de (2S, 3R)-1-halo-2-hydroxy-3-(amino protégé)-4-phénylthiobutanes de la formule générale (1) ou de leurs antipodes optiques. Ce procédé consiste à se débarrasser d'un composé de la formule générale (1) contaminé par des impuretés, ou de son antipode optique contaminé de façon similaire, en utilisant un solvant d'hydrocarbure aromatique permettant de transformer le composé ou l'antipode en cristal. Dans cette formule, X représente halogéno, et P?1¿ et P?2¿ représentent, chacun, indépendamment hydrogène ou un groupe amino protecteur, ou sont réunis pour former un groupe amino protecteur.
Designated States: HU, MX, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)