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1. WO1999004827 - METHOD FOR DETECTION OF FIBRIN CLOTS

Publication Number WO/1999/004827
Publication Date 04.02.1999
International Application No. PCT/AU1998/000582
International Filing Date 23.07.1998
Chapter 2 Demand Filed 24.02.1999
IPC
A61K 51/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
12characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
CPC
A61K 51/1251
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
12characterised by a special physical form, e.g. emulsion, microcapsules, liposomes ; , characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
1241particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
1244microparticles or nanoparticles, e.g. polymeric nanoparticles
1251micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 7/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Applicants
  • THE AUSTRALIAN NATIONAL UNIVERSITY [AU]/[AU] (AL, AM, AT, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CU, CY, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GH, GM, GN, GR, GW, HR, HU, ID, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW)
  • NAIR, Chenicheri, Hariharan [AU]/[AU] (UsOnly)
  • SHATS, Elena, Alexandra [AU]/[AU] (UsOnly)
  • BURCH, William, Martin [AU]/[AU] (UsOnly)
  • BROWITT, Rodney, James [AU]/[AU] (UsOnly)
  • SENDEN, Timothy, John [AU]/[AU] (UsOnly)
Inventors
  • NAIR, Chenicheri, Hariharan
  • SHATS, Elena, Alexandra
  • BURCH, William, Martin
  • BROWITT, Rodney, James
  • SENDEN, Timothy, John
Agents
  • SLATTERY, John, M.
Priority Data
PCT/AU97/0046724.07.1997AU
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR DETECTION OF FIBRIN CLOTS
(FR) PROCEDE DE DETECTION DE CAILLOTS DE FIBRINE
Abstract
(EN) A method for the detection of fibrin in a source, in particular the $i(in vivo) detection of a fibrin in a patient, the method comprising supplying to the source or patient an amount of a detectable reagent comprising a plurality of discrete particles, each of the particles comprising a plurality of layers of carbon and being capable of binding to fibrin; and detecting the presence of the particles in the source. The particles may also comprise a detectable marker encased in said plurality of layers of carbon, the presence of said marker being capable of detection in said source.
(FR) L'invention porte sur un procédé de détection de la fibrine dans une source, notamment de détection $i(in vivo) d'une fibrine chez un patient. Ce procédé consiste à introduire dans la source ou chez le patient une quantité d'un réactif détectable comprenant une pluralité de particules séparées, chacune de ces particules comprenant une pluralité de couches et pouvant se lier à la fibrine. L'invention porte également sur un procédé de détection de particules dans la source. Les particules peuvent également comporter un marqueur détectable renfermé dans la pluralité de couches de carbone, la présence de ce marqueur pouvant être détectée dans la source.
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