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1. (WO1999004826) METHOD FOR DETECTION OF FIBRIN CLOTS

Pub. No.:    WO/1999/004826    International Application No.:    PCT/AU1997/000467
Publication Date: Fri Feb 05 00:59:59 CET 1999 International Filing Date: Fri Jul 25 01:59:59 CEST 1997
IPC: A61K 51/12
Applicants: THE AUSTRALIAN NATIONAL UNIVERSITY
BURCH, William, Martin
BROWITT, Rodney, James
NAIR, Chenicheri, Hariharan
SHATS, Elena, Alexandra
Inventors: BURCH, William, Martin
BROWITT, Rodney, James
NAIR, Chenicheri, Hariharan
SHATS, Elena, Alexandra
Title: METHOD FOR DETECTION OF FIBRIN CLOTS
Abstract:
The invention relates to a method for labelling macromolecules with a detectable marker which is encompassed in a layer of carbon, and a method for labelling biological macromolecules with such a marker. Disclosed is a method for labelling proteins in vivo with this marker, and a method for detecting fibrin clots using radionuclides contained inside a carbon cage. Preferably the radiolabel is 99mTc encapsulated inside the carbon in the form of a nano-encapsulate.