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1. WO1999002556 - SEMAPHORIN RECEPTORS

Publication Number WO/1999/002556
Publication Date 21.01.1999
International Application No. PCT/US1998/014290
International Filing Date 08.07.1998
Chapter 2 Demand Filed 01.02.1999
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/705 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07K 14/7056
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
7056Lectin superfamily, e.g. CD23, CD72
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US]
Inventors
  • TESSIER-LAVIGNE, Marc
  • HE, Zhigang
  • CHEN, Hang
Agents
  • OSMAN, Richard, Aron
Priority Data
08/889,45808.07.1997US
08/936,13524.09.1997US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SEMAPHORIN RECEPTORS
(FR) RECEPTEURS DE SEMAPHORINE
Abstract
(EN) The invention provides methods and compositions relating to two classes of semaphorin receptors, SR1 and SR2. The polypeptides may be produced recombinantly from transformed host cells from the disclosed SR encoding nucleic acids or purified from human cells. The invention provides isolated SR hybridization probes and primers capable of specifically hybridizing with the disclosed SR genes, SR-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
(FR) La présente invention concerne des méthodes et des compositions liées à deux classes de récepteurs de sémaphorine, SR1 et SR2. Les polypeptides peuvent être obtenus par recombinaison à partir des cellules hôtes transformées des SR précités codant les acides nucléiques, ou purifiés à partir de cellules humaines. Par ailleurs, l'invention concerne des sondes et des amorces d'hybridation de SR isolées capables de s'hybrider spécifiquement avec les gènes SR décrits, des agents se liant spécifiquement aux SR, tels que les anticorps spécifiques, et enfin, des méthodes d'obtention et d'utilisation des compositions présentées dans l'établissement de diagnostics, en thérapie ainsi que dans l'industrie pharmaceutique.
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