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1. WO1999000147 - ANTIGENOMIC OLIGODEOXYNUCLEOTIDES FOR TREATMENT OF INFECTION BY NEGATIVE-STRANDED NONSEGMENTED RNA VIRUSES

Publication Number WO/1999/000147
Publication Date 07.01.1999
International Application No. PCT/US1998/013124
International Filing Date 26.06.1998
Chapter 2 Demand Filed 11.01.1999
IPC
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C12N 15/11 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C12N 15/1131
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
1131against viruses
C12N 2310/315
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2310Structure or type of the nucleic acid
30Chemical structure
31of the backbone
315Phosphorothioates
Applicants
  • FU, Zhen, Fang [--]/[US]
  • WICKSTROM, Eric [--]/[US]
  • DIETZSCHOLD, Bernhard [--]/[US]
  • KOPROWSKI, Hilary [--]/[US]
Inventors
  • FU, Zhen, Fang
  • WICKSTROM, Eric
  • DIETZSCHOLD, Bernhard
  • KOPROWSKI, Hilary
Agents
  • MONACO, Daniel, A.
Priority Data
60/051,36927.06.1997US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ANTIGENOMIC OLIGODEOXYNUCLEOTIDES FOR TREATMENT OF INFECTION BY NEGATIVE-STRANDED NONSEGMENTED RNA VIRUSES
(FR) OLIGODESOXYNUCLEOTIDES ANTIGENOMIQUES DESTINES AU TRAITEMENT DE L'INFECTION PAR DES VIRUS A ARN NON SEGMENTE A BRIN NEGATIF
Abstract
(EN) Oligodeoxynucleotides complementary to genomic RNA of a negative-stranded nonsegmented RNA virus are provided. Methods of inhibiting infection of cells by a negative-stranded nonsegmented RNA virus and treating animals infected with a negative-stranded nonsegmented RNA virus using these oligodeoxynucleotides are also provided.
(FR) La présente invention concerne des oligodésoxynucléotides complémentaires de l'ARN génomique d'un virus à ARN non segmenté à brin négatif. L'invention concerne des procédés permettant d'inhiber l'infection de cellules par des virus à ARN non segmenté à brin négatif et de traiter des animaux infectés par un virus à ARN non segmenté à brin négatif à l'aide de ces oligodésoxynucléotides.
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