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1. (WO1998053104) DETECTION OF RETROVIRAL SUBTYPES BASED UPON ENVELOPE SPECIFIC SEQUENCES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/053104 International Application No.: PCT/GB1998/001428
Publication Date: 26.11.1998 International Filing Date: 18.05.1998
Chapter 2 Demand Filed: 09.12.1998
IPC:
C07K 14/15 (2006.01) ,C12Q 1/70 (2006.01) ,G01N 33/569 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
08
RNA viruses
15
Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
70
involving virus or bacteriophage
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
Applicants:
MEDICAL RESEARCH COUNCIL [GB/GB]; 20 Park Crescent London W1N 4AL, GB (AllExceptUS)
STOYE, Jonathan, Paul [GB/GB]; GB (UsOnly)
WEISS, Robin, Anthony [GB/GB]; GB (UsOnly)
Inventors:
STOYE, Jonathan, Paul; GB
WEISS, Robin, Anthony; GB
Agent:
BRASNETT, Adrian, H. ; Mewburn Ellis York House 23 Kingsway London WC2B 6HP, GB
Priority Data:
9710154.716.05.1997GB
Title (EN) DETECTION OF RETROVIRAL SUBTYPES BASED UPON ENVELOPE SPECIFIC SEQUENCES
(FR) DETECTION DE SOUS-TYPES RETROVIRAUX BASEE SUR DES SEQUENCES SPECIFIQUES D'UNE ENVELOPPE
Abstract:
(EN) The present invention is based upon the finding that porcine endogenous retroviruses exist in two different subtypes, which we have termed PERV-A and PERV-B. The differences are reflected in sequence divergence in the envelope genes, and these differences may be used to provide nucleic acid and antibody probes which can distinguish between the two subtypes. This allows patterns of subtype transmission between cells, particularly porcine to human cells, to be monitored.
(FR) La présente invention est fondée sur la découverte selon laquelle des rétrovirus endogènes porcins présentent deux sous-types différents, que nous avons dénommés PERV-A et PERV-B. Ces différences se traduisent par une différence de séquences dans les gènes d'enveloppe, et peuvent être exploitées pour produire des sondes d'acide nucléique ou d'anticorps permettant de déterminer les deux sous-types. On peut ainsi surveiller les modes de transmission de sous-types entre cellules, notamment de la cellule porcine à la cellule humaine.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0981651US6100034JP2001527416 CA2289939DE000069825269GB2333102
AU1998074426