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1. (WO1998053104) DETECTION OF RETROVIRAL SUBTYPES BASED UPON ENVELOPE SPECIFIC SEQUENCES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/053104    International Application No.:    PCT/GB1998/001428
Publication Date: 26.11.1998 International Filing Date: 18.05.1998
Chapter 2 Demand Filed:    09.12.1998    
IPC:
C07K 14/15 (2006.01), C12Q 1/70 (2006.01), G01N 33/569 (2006.01)
Applicants: MEDICAL RESEARCH COUNCIL [GB/GB]; 20 Park Crescent London W1N 4AL (GB) (For All Designated States Except US).
STOYE, Jonathan, Paul [GB/GB]; (GB) (For US Only).
WEISS, Robin, Anthony [GB/GB]; (GB) (For US Only)
Inventors: STOYE, Jonathan, Paul; (GB).
WEISS, Robin, Anthony; (GB)
Agent: BRASNETT, Adrian, H.; Mewburn Ellis York House 23 Kingsway London WC2B 6HP (GB)
Priority Data:
9710154.7 16.05.1997 GB
Title (EN) DETECTION OF RETROVIRAL SUBTYPES BASED UPON ENVELOPE SPECIFIC SEQUENCES
(FR) DETECTION DE SOUS-TYPES RETROVIRAUX BASEE SUR DES SEQUENCES SPECIFIQUES D'UNE ENVELOPPE
Abstract: front page image
(EN)The present invention is based upon the finding that porcine endogenous retroviruses exist in two different subtypes, which we have termed PERV-A and PERV-B. The differences are reflected in sequence divergence in the envelope genes, and these differences may be used to provide nucleic acid and antibody probes which can distinguish between the two subtypes. This allows patterns of subtype transmission between cells, particularly porcine to human cells, to be monitored.
(FR)La présente invention est fondée sur la découverte selon laquelle des rétrovirus endogènes porcins présentent deux sous-types différents, que nous avons dénommés PERV-A et PERV-B. Ces différences se traduisent par une différence de séquences dans les gènes d'enveloppe, et peuvent être exploitées pour produire des sondes d'acide nucléique ou d'anticorps permettant de déterminer les deux sous-types. On peut ainsi surveiller les modes de transmission de sous-types entre cellules, notamment de la cellule porcine à la cellule humaine.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)