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1. (WO1998053088) IMPROVED TRANSAMINASE BIOTRANSFORMATION PROCESS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/053088 International Application No.: PCT/US1998/010169
Publication Date: 26.11.1998 International Filing Date: 19.05.1998
Chapter 2 Demand Filed: 15.12.1998
IPC:
C12N 9/10 (2006.01) ,C12N 9/88 (2006.01) ,C12P 13/04 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
88
Lyases (4.)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
13
Preparation of nitrogen-containing organic compounds
04
Alpha- or beta-amino acids
Applicants:
NSC TECHNOLOGIES L.L.C. [US/US]; 601 East Kensington Mount Prospect, IL 60056, US (AllExceptUS)
FOTHERINGHAM, Ian, G. [US/US]; US (UsOnly)
Inventors:
FOTHERINGHAM, Ian, G.; US
Agent:
GOLDEN, Matthew, J.; Fitzpatrick, Cella, Harper & Scinto 30 Rockefeller Plaza New York, NY 10112-3801 , US
Priority Data:
08/858,11119.05.1997US
Title (EN) IMPROVED TRANSAMINASE BIOTRANSFORMATION PROCESS
(FR) PROCEDE AMELIORE DE BIOTRANSFORMATION A L'AIDE DE TRANSAMINASE
Abstract:
(EN) A process for making natural and unnatural amino acids which comprises reacting a first amino acid, a keto acid and a transaminase enzyme under conditions appropriate to produce a second amino acid and pyruvate; reacting the pyruvate with acetolactate synthase under conditions appropriate to produce a compound that does not react with the transaminase enzyme and separating the second amino acid.
(FR) Procédé permettant de produire des acides aminés naturels et synthétiques, qui consiste à faire réagir un premier acide aminé, un céto-acide et une enzyme transaminase dans des conditions appropriées pour produire un second acide aminé et du pyruvate, à faire réagir le pyruvate avec de l'acétolactate synthase dans des conditions appropriées pour produire un composé qui ne réagit pas avec l'enzyme transaminase, et à séparer le second acide aminé.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0983372JP2002514921 CA2290065AU1998075782