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1. (WO1998053083) GENE SILENCING
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/053083 International Application No.: PCT/GB1998/001450
Publication Date: 26.11.1998 International Filing Date: 20.05.1998
Chapter 2 Demand Filed: 20.10.1998
IPC:
C12N 15/63 (2006.01) ,C12N 15/82 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
82
for plant cells
Applicants:
ZENECA LIMITED [GB/GB]; 15 Stanhope Gate London W1Y 6LN, GB (AllExceptUS)
GRIERSON, Donald [GB/GB]; GB (UsOnly)
LOWE, Alexandra, Louise [GB/GB]; GB (UsOnly)
HAMILTON, Andrew, John [GB/GB]; GB (UsOnly)
Inventors:
GRIERSON, Donald; GB
LOWE, Alexandra, Louise; GB
HAMILTON, Andrew, John; GB
Agent:
HUSKISSON, Frank, Mackie ; Zeneca Agrochemicals Intellectual Property Dept. Jealott's Hill Research Station P.O. Box 3538 Bracknell, Berkshire RG42 6YA, GB
Priority Data:
9710475.621.05.1997GB
Title (EN) GENE SILENCING
(FR) INHIBITION D'UN GENE
Abstract:
(EN) Constructs and methods for enhancing the inhibition of a target gene within an organism involve inserting into the gene silencing vector an inverted repeat sequence of all or part of a polynucleotide region within the vector. The inverted repeat sequence may be a synthetic polynucleotide sequence or comprise a modified natural polynucleotide sequence.
(FR) On décrit des constructions et des procédés servant à accentuer l'inhibition d'un gène cible dans un organisme, qui consistent à introduire dans le vecteur d'inhibition du gène une séquence répétée inverse de toute ou partie d'une région polynucléotidique située à l'intérieur du vecteur. La séquence répétée inverse peut être une séquence polynucléotidique synthétique ou comprendre une séquence polynucléotidique modifiée.
front page image
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0983370EP1352963US20030175965JP2001525680 CA2286480DE000069818252
PT983370AU1998074442DK0983370