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1. (WO1998052974) ANTIBODIES TO $i(CRYPTOSPORIDIUM)
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052974 International Application No.: PCT/AU1998/000368
Publication Date: 26.11.1998 International Filing Date: 19.05.1998
Chapter 2 Demand Filed: 03.12.1998
IPC:
C07K 16/20 (2006.01) ,G01N 33/569 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
20
from protozoa
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
Applicants:
MACQUARIE RESEARCH LTD. [AU/AU]; Building W3A Ground floor Macquarie University, NSW 2106, AU (AllExceptUS)
AUSTRALIAN WATER TECHNOLOGIES PTY. LTD. [AU/AU]; Level 1 339-341 Pitt Street Sydney, NSW 2000, AU (AllExceptUS)
VESEY, Graham [GB/AU]; AU (UsOnly)
WEIR, Christopher [AU/AU]; AU (UsOnly)
WILLIAMS, Keith, Leslie [AU/AU]; AU (UsOnly)
SLADE, Martin, Basil [AU/AU]; AU (UsOnly)
VEAL, Duncan [GB/AU]; AU (UsOnly)
Inventors:
VESEY, Graham; AU
WEIR, Christopher; AU
WILLIAMS, Keith, Leslie; AU
SLADE, Martin, Basil; AU
VEAL, Duncan; AU
Agent:
F.B. RICE & CO.; 605 Darling Street Balmain, NSW 2041, AU
Priority Data:
PO 696219.05.1997AU
PO 824225.07.1997AU
Title (EN) ANTIBODIES TO $i(CRYPTOSPORIDIUM)
(FR) ANTICORPS DIRIGES CONTRE CRYPTOSPORIDIUM
Abstract:
(EN) A method of producing IgG1 subclass antibodies reactive to the surface of $i(Crystosporidium oocysts), the method comprising: (a) separating at least a protion of the $i(Cryptosporidium oocyst) wall from the internal sporozoites to form an oocyst-wall preparation; (b) treating the separated oocyst-wall preparation so as to obtain an oocyst antigen preparation capable of eliciting a detectable IgG1 immune response in an animal to the surface of the oocyst; (c) immunising an animal with the oocyst antigen preparation so as to elicit an IgG1 immune response in the animal; and (d) obtaining from the animal IgG1 antibodies reactive to the surface of $i(Cryptosporidium oocysts). IgG1 antibodies reactive to the surface of $i(Cryptosporidium oocysts).
(FR) L'invention concerne un procédé de production d'anticorps de la sous-classe d'IgG1, réactifs à l'encontre de la surface des oocyste de $i(Cryptosporidium). Ledit procédé consiste à: (a) séparer au moins une partie de la paroi de l'oocyste de $i(Cryptosporidium) des sporozoïtes internes pour former une préparation à base de paroi d'oocyste; (b) traiter la préparation de paroi d'oocyste séparée pour produire une préparation antigène d'oocyste capable de produire une réponse immunitaire d'IgG1 chez un animal, dirigée contre la surface de l'oocyste; (c) immuniser un animal à l'aide de la préparation à base de paroi d'oocyste de sorte qu'une réponse immunitaire d'IgG1 soit produite chez l'animal; (d) prélever sur l'animal des anticorps IgG1 réactifs à l'encontre de la surface des oocystes de $i(Cryptosporidium). L'invention porte également sur les anticorps IgG1 réactifs à l'encontre de la surface des oocystes de $i(Cryptosporidium).
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0991667US6777222AU1998075117