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1. (WO1998052968) METHOD FOR IDENTIFICATION OF MODIFIED RECEPTOR LIGANDS AND METHODS OF USE THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/052968 International Application No.: PCT/US1998/010671
Publication Date: 26.11.1998 International Filing Date: 21.05.1998
Chapter 2 Demand Filed: 21.12.1998
IPC:
G01N 33/566 (2006.01) ,G01N 33/74 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
566
using specific carrier or receptor proteins as ligand binding reagent
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
74
involving hormones
Applicants:
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES [US/US]; 10010 N. Torrey Pines Road La Jolla, CA 92037, US
Inventors:
FORMAN, Barry, M.; US
Agent:
HAILE, Lisa, A.; Fish & Richardson P.C. Suite 1400 4225 Executive Square La Jolla, CA 92037, US
Priority Data:
08/859,77121.05.1997US
Title (EN) METHOD FOR IDENTIFICATION OF MODIFIED RECEPTOR LIGANDS AND METHODS OF USE THEREFOR
(FR) PROCEDE D'IDENTIFICATION DE LIGANDS DE RECEPTEURS MODIFIES ET PROCEDE D'UTILISATION DE CES DERNIERS
Abstract:
(EN) Novel modified receptor proteins and ligands that bind to these receptor proteins are provided. Also included in the present invention are methods of identifying ligands that bind to such modified receptor proteins and methods of use of the modified receptor to modulate the expression of an exogenous gene in a mammalian subject.
(FR) La présente invention concerne de nouvelles protéines réceptrices modifiées et des ligands qui se lient à ces protéines réceptrices. L'invention se rapporte également à des procédés d'identification de ligands qui se lient à ces protéines réceptrices modifiées et à des procédés d'utilisation du récepteur modifié pour moduler l'expression d'un gène exogène chez un mammifère.
Designated States: CA, JP
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)