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1. (WO1998052941) PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052941 International Application No.: PCT/US1998/011684
Publication Date: 26.11.1998 International Filing Date: 22.05.1998
Chapter 2 Demand Filed: 16.12.1998
IPC:
C07D 401/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
Applicants:
G.D. SEARLE AND CO. [US/US]; P.O. Box 5110 Chicago, IL 60680, US (AllExceptUS)
HANSON, Gunnar, J. [US/US]; US (UsOnly)
LIAO, Shuyuan [CN/US]; US (UsOnly)
Inventors:
HANSON, Gunnar, J.; US
LIAO, Shuyuan; US
Agent:
ROEDEL, John, K., Jr. ; Senniger, Powers, Leavitt & Roedel 16th floor One Metropolitan Square St. Louis, MO 63102, US
BEIL, Hans, Chr.; Adelonstrasse 58 Postfach 80 01 40 D-65901 Frankfurt am Main, DE
Priority Data:
60/047,56922.05.1997US
Title (EN) PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS
(FR) DERIVES DE PYRAZOLE COMME INHIBITEURS DE KINASE p38
Abstract:
(EN) A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula (I) wherein Q, R1, R2, R3 and R4 are as described in the specification.
(FR) L'invention concerne une classe de dérivés de pyrazole à utiliser dans le traitement de troubles ayant la kinase p38 comme médiateur. Les composés d'intérêt particulier sont définis par la formule (I), formule dans laquelle Q, R1, R2, R3 et R4 sont décrits dans les pièces descriptives de l'invention.
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Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1019394JP2002502380 CA2288787AU1998077268