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1. (WO1998052939) CIS-DISUBSTITUTED AMINOCYCLOALKYL-PYRROLIDINE DERIVATIVES

Pub. No.:    WO/1998/052939    International Application No.:    PCT/JP1998/002219
Publication Date: Fri Nov 27 00:59:59 CET 1998 International Filing Date: Thu May 21 01:59:59 CEST 1998
IPC: C07D 207/09
C07D 207/10
C07D 207/20
C07D 207/24
C07D 207/26
C07D 207/273
C07D 207/38
C07D 401/04
C07D 498/08
Applicants: DAIICHI PHARMACEUTICAL CO., LTD.

TAKEMURA, Makoto

TAKAHASHI, Hisashi

SUGITA, Kazuyuki

OHKI, Hitoshi

MIYAUCHI, Satoru

MIYAUCHI, Rie

Inventors: TAKEMURA, Makoto

TAKAHASHI, Hisashi

SUGITA, Kazuyuki

OHKI, Hitoshi

MIYAUCHI, Satoru

MIYAUCHI, Rie

Title: CIS-DISUBSTITUTED AMINOCYCLOALKYL-PYRROLIDINE DERIVATIVES
Abstract:
Antibacterial agents which are excellent in antibacterial activity and safety and comprise compounds represented by general formula (I), their salts, or hydrates of the same, wherein R1 represents hydrogen or alkyl; R2 represents hydrogen or alkyl; R?3 and R5¿ represent each hydrogen; R4 represents hydroxy, halogeno, carbamoyl, alkyl, alkoxy or alkylthio; R?6 and R7¿ represent each hydrogen or alkyl; n is an integer of from 1 to 3; R4 and the substituent on the pyrrolidine ring of general formula (III) are arranged at the cis-configuration; and Q is a partial structure represented by general formula (a).