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1. (WO1998052894) CYCLOHEXANEDIOL DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/052894    International Application No.:    PCT/EP1998/002762
Publication Date: 26.11.1998 International Filing Date: 12.05.1998
Chapter 2 Demand Filed:    08.12.1998    
IPC:
C07C 35/17 (2006.01), C07F 7/18 (2006.01)
Applicants: F.HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH)
Inventors: BAUER, Franz; (CH).
COURTNEY, Lawrence, F.; (US)
Agent: KJELLSAA-BERGER, Hanny; Grenzacherstrasse 124, CH-4070 Basel (CH)
Priority Data:
97108355.5 23.05.1997 EP
Title (EN) CYCLOHEXANEDIOL DERIVATIVES
(FR) DERIVES CYCLOHEXANEDIOL
Abstract: front page image
(EN)The compound, (E)-(1R,3R)-5-[(R)-11-hydroxy-7,11-dimethyl-dodec-2-enylidene]-cyclohexane-1,3-diol of formula (I) is useful in the treatment or prevention of hyperproliferative skin diseases, particularly psoriasis, basal cell carcinomas, disorders of keratinization and keratosis; or for reversing the conditions associated with photodamage.
(FR)L'invention concerne le composé (E)-(1R, 3R)-5-[(R)-11-hydroxy-7,11-diméthyl-dodec-2-énylidène]-cyclohexane-1,3-diol représenté par la formule I et convenant particulièrement au traitement ou à la prévention de maladies hyperprolifératives de la peau, particulièrement le psoriasis, le carcinome basocellulaire, les troubles de la kératinisation ou la kératose ou pour inverser le cours de maladies liées aux effets nocifs du soleil.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)