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1. (WO1998052620) COLLAGEN-LIKE POLYMERS WITH CELL BINDING ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/052620    International Application No.:    PCT/EP1998/002857
Publication Date: 26.11.1998 International Filing Date: 14.05.1998
Chapter 2 Demand Filed:    27.11.1998    
IPC:
A61L 27/22 (2006.01), A61L 27/34 (2006.01), A61L 31/04 (2006.01), A61L 31/10 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Schwarzwaldallee 215, CH-4058 Basel (CH) (For All Designated States Except US).
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION [AU/AU]; Limestone Avenue, Campbell, ACT 2602 (AU) (For All Designated States Except US).
STEELE, John, Gerard [AU/AU]; (AU) (For US Only).
JOHNSON, Graham [AU/AU]; (AU) (For US Only).
GOODMAN, Murray [US/CA]; (CA) (For US Only).
GRIESSER, Hans, Jörg [CH/AU]; (AU) (For US Only).
MCLEAN, Keith, Michael [AU/AU]; (AU) (For US Only).
BEUMER, Gerrit, Jan [NL/NL]; (NL) (For US Only)
Inventors: STEELE, John, Gerard; (AU).
JOHNSON, Graham; (AU).
GOODMAN, Murray; (CA).
GRIESSER, Hans, Jörg; (AU).
MCLEAN, Keith, Michael; (AU).
BEUMER, Gerrit, Jan; (NL)
Agent: BECKER, Konrad; Novartis AG, Patent- und Markenabteilung, Lichtstrasse 35, CH-4002 Basel (CH)
Priority Data:
6862/97 16.05.1997 AU
6842/97 16.05.1997 AU
Title (EN) COLLAGEN-LIKE POLYMERS WITH CELL BINDING ACTIVITY
(FR) POLYMERES DU TYPE COLLAGENE A ACTIVITE DE LIAISON CELLULAIRE
Abstract: front page image
(EN)The invention is essentially directed to a biocompatible material comprising a bulk material which has covalently bound to a surface or surfaces thereof one or more biopolymer compounds, said biopolymer compounds comprising at least one peptoid residue. The biopolymer compounds are most preferably polymer compounds comprising the sequence of the formula (I): -(Gly-Pro-Nleu)(Y)-, wherein (y) denotes $m(G)9. Also disclosed is a method of binding biopolymer compounds to a bulk material, which biopolymer compounds comprise at least one peptoid residue, as well as primary amine groups, the method comprising the steps of: (a) providing aldehyde or carboxyl groups on a surface or surfaces of said bulk material; (b) reacting said primary amine groups with aldehyde or carboxyl groups to form covalent bonds.
(FR)L'invention concerne essentiellement une matière biocompatible comprenant une matière en vrac qui a lié par covalence à une ou plusieurs de ses surfaces un ou plusieurs composés biopolymères, lesdits composés biopolymères comprenant au moins un reste peptoïde. Les composés biopolymères sont de préférence des composés polymères comprenant la séquence de la formule (I): -(Gly-Pro-Nleu)(y)-, dans laquelle (y) à la signification $m(G) 9. Un procédé de liaison de composés biopolymères à une matière en vrac fait aussi l'objet de cette invention. Lesdits composés biopolymères comprennent au moins un reste peptoïde, ainsi que des groupes amino primaires. Le procédé consiste (a) à placer des groupes aldéhyde ou carboxyle sur une ou plusieurs surfaces de ladite matière en vrac; (b) à faire réagir lesdits groupes amino primaires avec des groupes aldéhyde ou carboxyle pour former des liaisons covalentes.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)