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1. (WO1998052609) SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052609 International Application No.: PCT/GB1998/001444
Publication Date: 26.11.1998 International Filing Date: 19.05.1998
Chapter 2 Demand Filed: 07.12.1998
IPC:
A61K 41/00 (2006.01) ,A61K 47/48 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41
Medicinal preparations obtained by treating materials with wave energy or particle radiation
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
Applicants:
NYCOMED IMAGING AS [NO/NO]; Nycoveien 1-2 N-0401 Oslo, NO (AllExceptUS)
ALFHEIM, Jan, Alan [NO/NO]; NO (UsOnly)
HENRICHS, Paul, Mark [US/US]; US (UsOnly)
HOHENSCHUH, Eric, Paul [US/US]; US (UsOnly)
JOHANNESEN, Edvin, Wilhelm [NO/NO]; NO (UsOnly)
SANDERSON, William, Anthony [GB/US]; US (UsOnly)
SNOW, Robert, Allen [CA/US]; US (UsOnly)
Inventors:
ALFHEIM, Jan, Alan; NO
HENRICHS, Paul, Mark; US
HOHENSCHUH, Eric, Paul; US
JOHANNESEN, Edvin, Wilhelm; NO
SANDERSON, William, Anthony; US
SNOW, Robert, Allen; US
Agent:
FRANK B. DEHN & CO.; 179 Queen Victoria Street London EC4V 4EL, GB
Priority Data:
9710049.919.05.1997GB
Title (EN) SONODYNAMIC THERAPY USING AN ULTRASOUND SENSITIZER COMPOUND
(FR) THERAPIE SONODYNAMIQUE METTANT EN OEUVRE UN COMPOSE SENSIBILISANT ULTRASONORE
Abstract:
(EN) The invention provides a method of treatment of the human or animal body by sonodynamic therapy in which a sensitizer agent is administered to said body and said body is exposed to ultrasound to achieve a cytopathogenic effect at a site therein, wherein the said sensitizer agent is a physiologically tolerable substance which is capable of enhancing the cytopathogenic efficacy of said sonodynamic therapy. Preferably, the sensitizer agent is a water-soluble polymer compound or a conjugate thereof.
(FR) L'invention concerne un procédé de traitement du corps humain ou animal au moyen d'une thérapie sonodynamique. Pour réaliser le traitement, une substance sensibilisante est administrée sur un site dudit corps, lequel est ensuite exposé à des ultrasons pour y provoquer un effet cytopathogène. Cette substance sensibilisante est une substance physiologiquement tolérable, capable d'accroître l'efficacité cytopathogène de ladite thérapie sonodynamique. De préférence, la substance sensibilisante est un composé polymère soluble dans l'eau ou un conjugué dudit composé polymère.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0979104US6498945JP2001525845 DE000069826263AU1998074438