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1. (WO1998052591) GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052591 International Application No.: PCT/US1998/009056
Publication Date: 26.11.1998 International Filing Date: 04.05.1998
Chapter 2 Demand Filed: 16.12.1998
IPC:
C07K 14/71 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
71
for growth factors; for growth regulators
Applicants:
CEPHALON INC. [US/US]; 145 Brandywine Parkway West Chester, PA 19380, US
Inventors:
IBANEZ, Carlos, F.; SE
ARUMAE, Urmas; FI
SARIOLA, Hannu; FI
SUVANTO, Petro; FI
TRUPP, Miles; SE
SAARMA, Mart; FI
Agent:
MILLER, Suzanne, E. ; Woodcock Washburn Kurtz Mackiewicz & Norris LLP 46th floor One Liberty Place Philadelphia, PA 19103, US
Priority Data:
08/861,99022.05.1997US
Title (EN) GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS
(FR) RECEPTEURS DU FACTEUR NEUROTROPHIQUE DERIVE DE LIGNES DE CELLULES GLIALES
Abstract:
(EN) Receptors for Glial Cell Line-Derived Neurotrophic Factor (GDNF), their cellular expression, isolation, biochemical characterization, and sequences are disclosed. c-RET is disclosed as one receptor for GDNF; additional novel receptors are also disclosed. The preparation of monoclonal antibodies directed against GDNF is also disclosed.
(FR) Récepteurs du facteur neurotrophique dérivé de lignes de cellules gliales (GDNF), leur expression cellulaire, leur isolation, leur caractérisation biochimique et leurs séquences. L'invention concerne c-RET en tant qu'un récepteur de GDNF, ainsi que de nouveaux récepteurs supplémentaires. Elle concerne également la préparation d'anticorps monoclonaux dirigés contre GDNF.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NO19995691MXPA/a/1999/010773KR1020010012826EP1007072JP2001527418 CA2290426
NZ501199AU1998072825