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1. (WO1998052574) VITAMIN D ANALOGUES AND THEIR NEURONAL EFFECTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1998/052574    International Application No.:    PCT/US1998/010480
Publication Date: 26.11.1998 International Filing Date: 21.05.1998
Chapter 2 Demand Filed:    13.11.1998    
IPC:
A61K 31/59 (2006.01)
Applicants: CEPHALON, INC. [US/US]; 145 Brandywine Parkway West Chester, PA 19380 (US).
LEO PHARMACEUTICAL PRODUCTS LTD. A/S [DK/DK]; Industriparken 55 DK-2750 Ballerup (DK)
Inventors: CARSWELL, Susan; (US).
DOBRZANSKI, Pawel; (US).
BINDERUP, Lise; (DK).
BJÖRKLING, Fredrik; (SE).
MILLER, Matthew, S.; (US)
Agent: CREASON, Gary, L.; Fish & Richardson P.C. 225 Franklin Street Boston, MA 02110-2804 (US)
Priority Data:
60/047,391 22.05.1997 US
09/082,762 21.05.1998 US
Title (EN) VITAMIN D ANALOGUES AND THEIR NEURONAL EFFECTS
(FR) ANALOGUES DE VITAMINE D ET LEURS EFFETS SUR LES NEURONES
Abstract: front page image
(EN)The present invention is directed, $i(inter alia), to methods of utilizing low calcemic vitamin D analogues. Particularly, the present invention is directed to using low calcemic vitamin D analogues to treat neurodegenerative diseases and disorders, to facilitate endogenous production of neurotrophic factors, to inhibit the degradation, dysfunction or loss of neural cells and/or to enhance the phenotype of neural cells or neuronal processes.
(FR)La présente invention a trait, entre autres, à des procédés d'utilisation d'analogues de vitamine D à faible teneur en calcium. En particulier, la présente invention a trait à l'utilisation d'analogues de vitamine D à faible teneur en calcium pour traiter des maladies et des troubles neurodégénératifs, pour faciliter la production endogène de facteurs neurotrophiques, pour inhiber la dégradation, le dysfonctionnement ou la perte de cellules nerveuses et/ou améliorer le phénotype de cellules nerveuses ou de processus neuronaux.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, UZ, VN, YU, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)