Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1998052560) METHOD FOR INCREASING THE CONCENTRATION OF ASCORBIC ACID IN BRAIN TISSUES OF A SUBJECT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052560 International Application No.: PCT/US1998/010608
Publication Date: 26.11.1998 International Filing Date: 21.05.1998
Chapter 2 Demand Filed: 21.12.1998
IPC:
A61K 31/34 (2006.01) ,A61K 31/375 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
34
having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
365
Lactones
375
Ascorbic acid, i.e. vitamin C; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH [US/US]; 1275 York Avenue New York, NY 10021, US (AllExceptUS)
AGUS, David, B. [US/US]; US (UsOnly)
VERA, Juan, C. [CL/US]; US (UsOnly)
GOLDE, David, W. [US/US]; US (UsOnly)
Inventors:
AGUS, David, B.; US
VERA, Juan, C.; US
GOLDE, David, W.; US
Agent:
WHITE, John, P.; Cooper & Dunham LLP 1185 Avenue of the Americas New York, NY 10036, US
Priority Data:
60/047,27121.05.1997US
60/067,18501.12.1997US
Title (EN) METHOD FOR INCREASING THE CONCENTRATION OF ASCORBIC ACID IN BRAIN TISSUES OF A SUBJECT
(FR) PROCEDE PERMETTANT D'AUGMENTER LA CONCENTRATION D'ACIDE ASCORBIQUE DANS LES TISSUS CEREBRAUX D'UN INDIVIDU
Abstract:
(EN) This invention provides a method for increasing the ascorbic acid concentration in brain tissues of a subject which comprises administering to the subject an amount of dehydroascorbic acid effective to increase the concentration of ascorbic acid in brain tissues. This invention also provides that the dehydroascorbic acid enters the tissues through the facilitative glucose transporter.
(FR) Cette invention concerne un procédé permettant d'augmenter la concentration d'acide ascorbique dans les tissus cérébraux d'un individu. Ce procédé consiste à administrer à l'individu une quantité d'acide déhydroascorbique efficace pour augmenter la concentration d'acide ascorbique dans les tissus cérébraux. Cette invention stipule également que l'acide déhydroascorbique pénètre dans les tissus par l'intermédiaire du vecteur de transport du glucose.
Designated States: CA, JP, US
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0983062US20010053793US6221904US6262111US20020022654US20040002540
JP2002513383 CA2290381