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1. (WO1998052558) INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052558 International Application No.: PCT/US1998/010375
Publication Date: 26.11.1998 International Filing Date: 21.05.1998
Chapter 2 Demand Filed: 22.12.1998
IPC:
A61K 31/341 (2006.01) ,A61K 31/381 (2006.01) ,A61K 31/40 (2006.01) ,A61K 31/433 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
34
having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
341
not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
38
having sulfur as a ring hetero atom
381
having five-membered rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
433
Thiadiazoles
Applicants:
BAYER CORPORATION [US/US]; 400 Morgan Lane West Haven, CT 06516-4175, US (AllExceptUS)
RANGES, Gerald [US/US]; US (UsOnly)
SCOTT, William [US/US]; US (UsOnly)
BOMBARA, Michael [US/US]; US (UsOnly)
RAUNER, Deborah [US/US]; US (UsOnly)
REDMAN, Aniko [HU/US]; US (UsOnly)
SMITH, Roger [CA/US]; US (UsOnly)
PAULSEN, Holger [DE/DE]; DE (UsOnly)
CHEN, Jinshan [CN/US]; US (UsOnly)
GUNN, David [US/US]; US (UsOnly)
RENICK, Joel [US/US]; US (UsOnly)
Inventors:
RANGES, Gerald; US
SCOTT, William; US
BOMBARA, Michael; US
RAUNER, Deborah; US
REDMAN, Aniko; US
SMITH, Roger; US
PAULSEN, Holger; DE
CHEN, Jinshan; US
GUNN, David; US
RENICK, Joel; US
Agent:
SHUBIN, Harry, B. ; Millen, White, Zelano & Branigan, P.C. Suite 1400 2200 Clarendon Boulevard Arlington, VA 22201, US
Priority Data:
08/863,02223.05.1997US
Title (EN) INHIBITION OF p38 KINASE ACTIVITY BY ARYL UREAS
(FR) INHIBITION DE L'ACTIVITE DE LA p38 KINASE PAR DES ARYL-UREES
Abstract:
(EN) This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.
(FR) Cette invention se rapporte à un groupe d'aryl-urées utilisées pour traiter des troubles liés à la production de cytokines, autres que le cancer et les maladies liées à la présence d'enzymes protéolytiques autres que le cancer, ainsi qu'à des compositions pharmaceutiques destinées à ce type de thérapie.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP1019040JP2001526687 CA2290520AU1998075854DK1019040