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1. (WO1998052545) PHARMACEUTICAL COMPOSITIONS OF FLURBIPROFEN AND BURN-MASKING AGENT FOR TREATING SORE THROAT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1998/052545 International Application No.: PCT/EP1998/003180
Publication Date: 26.11.1998 International Filing Date: 22.05.1998
Chapter 2 Demand Filed: 10.12.1998
IPC:
A61K 9/00 (2006.01) ,A61K 45/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants:
THE BOOTS COMPANY PLC [GB/GB]; 1 Thane Road West Nottingham NG2 3AA, GB (AllExceptUS)
BARRETT, David, Michael [GB/GB]; GB (UsOnly)
JONES, Huw, Lyn [GB/GB]; GB (UsOnly)
JONES, Idwal [GB/GB]; GB (UsOnly)
SMITH, Carl, Simon [GB/GB]; GB (UsOnly)
Inventors:
BARRETT, David, Michael; GB
JONES, Huw, Lyn; GB
JONES, Idwal; GB
SMITH, Carl, Simon; GB
Agent:
THACKER, Michael, Anthony; The Boots Company plc Group Patents Dept. D31 1 Thane Road West Nottingham NG2 3AA, GB
Priority Data:
9710525.822.05.1997GB
9710632.222.05.1997GB
Title (EN) PHARMACEUTICAL COMPOSITIONS OF FLURBIPROFEN AND BURN-MASKING AGENT FOR TREATING SORE THROAT
(FR) COMPOSITIONS PHARMACEUTIQUES A BASE DE FLURBIPROFENE ET D'UN AGENT DE MASQUAGE DE BRULURE POUR LE TRAITEMENT DE L'ANGINE
Abstract:
(EN) The present invention relates to pharmaceutical compositions comprising a combination of flurbiprofen with (a) a therapeutically effective amount of one or more active ingredients selected from an antihistamine, a cough suppressant, a decongestant, an expectorant, a muscle relaxant, a centrally acting analgesic, a local anaesthetic, an antibacterial compound, an antiviral compound, an antibiotic compound, an antifungal compound, minerals and vitamins and/or (b) a burn-masking amount of an agent which has a warming effect on the mucosa of the throat for use in the treatment of cold and flu symptoms including particularly sore throat. The treatment comprises the administration to a patient in need thereof of a pharmaceutical composition in the form of a masticable or suckable solid dosage form or a liquid or spray which releases the flurbiprofen and active ingredient(s) and/or burn-masking agent in the oral cavity so as to deliver the active components to the surface of the sore throat.
(FR) La présente invention concerne des compositions pharmaceutiques comprenant une combinaison de flurbiprofène avec (a) une quantité efficace sur le plan thérapeutique d'un ou de plusieurs ingrédients actifs sélectionnés dans le groupe formé par un antihistaminique, un antitussif, un décongestionnant, un expectorant, un myorelaxant, un analgésique à action centrale, un anesthésique local, un composé antibactérien, un composé antiviral, un composé antibiotique, un composé antifongique, des minéraux et des vitamines; et/ou (b) un agent en quantité permettant de masquer la brûlure, agent exerçant un effet de réchauffement sur les muqueuses de la gorge; les compositions sont destinées à s'utiliser dans le traitement de symptômes du rhume et de la grippe, y compris et notamment l'angine. Le traitement consiste en l'administration à un patient d'une composition pharmaceutique sous la forme d'une dose solide à mâcher ou à sucer ou de liquide ou de substance à pulvériser libérant le flurbiprofène et les ingrédients actifs; et/ou en l'administration d'un agent de soulagement de brûlures dans la cavité buccale de manière à déposer les composants actifs à la surface de la gorge présentant une angine.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1998079167