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1. (WO1998051794) ANTIMICROBIAL PEPTIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1998/051794 International Application No.: PCT/US1998/009796
Publication Date: 19.11.1998 International Filing Date: 14.05.1998
Chapter 2 Demand Filed: 10.12.1998
IPC:
C07K 14/47 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants:
OLSEN, Henrik, S. [DK/US]; US (UsOnly)
RUBEN, Steven, M. [US/US]; US (UsOnly)
HUMAN GENOME SCIENCES, INC. [US/US]; 9410 Key West Avenue Rockville, MD 20850, US (AllExceptUS)
Inventors:
OLSEN, Henrik, S.; US
RUBEN, Steven, M.; US
Agent:
STEFFE, Eric, K.; Sterne, Kessler, Goldstein & Fox P.L.L.C. Suite 600 1100 New York Avenue, N.W. Washington, DC 20005-3934 , US
Priority Data:
60/046,41514.05.1997US
Title (EN) ANTIMICROBIAL PEPTIDE
(FR) PEPTIDE ANTIMICROBIEN
Abstract:
(EN) The present invention relates to a novel human antimicrobial peptide which is a member of the defensin superfamily. In particular, isolated nucleic acid molecules are provided encoding the human antimicrobial peptide. Antimicrobial peptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic methods for detecting disorders related to the immune system and therapeutic methods for such disorders.
(FR) La présente invention concerne un nouveau peptide antimicrobien humain qui est un membre de la superfamille des défensines. L'invention concerne en particulier des molécules d'acide nucléique isolées codant le peptide antimicrobien humain. L'invention concerne en outre des peptides antimicrobiens, ainsi que des vecteurs, des cellules hôtes et des méthodes de recombinaison permettant leur production. L'invention concerne enfin des méthodes diagnostiques destinées à la détection de troubles liés au système immunitaire et des méthodes thérapeutiques destinées au traitement de tels troubles.
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Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, GH, GM, GW, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)